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Index > Protein center > Hnrnpk(Gene name) > Mouse
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  • Hnrnpk (Gene name),
  • Heterogeneous nuclear ribonucleoprotein K (Protein name ),  HNRPK_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Hnrnpk(Hnrpk);
    Protein name:
    Heterogeneous nuclear ribonucleoprotein K(hnRNP K);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Identified in the spliceosome C complex (By similarity). Interacts with ANKRD28 and RBM42. Interacts with DDX1 (By similarity). Interacts with ZIK1.
    Function:
    One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA.
    Subcellular Location:
    Cytoplasm Nucleus nucleoplasm
    Protein Attributes:
    Sequence length:
    463
    Sequence:
    50:
    METEQPEETF | PNTETNGEFG | KRPAEDMEEE | QAFKRSRNTD | EMVELRILLQ | 
    100:
    SKNAGAVIGK | GGKNIKALRT | DYNASVSVPD | SSGPERILSI | SADIETIGEI | 
    150:
    LKKIIPTLEE | GLQLPSPTAT | SQLPLESDAV | ECLNYQHYKG | SDFDCELRLL | 
    200:
    IHQSLAGGII | GVKGAKIKEL | RENTQTTIKL | FQECCPHSTD | RVVLIGGKPD | 
    250:
    RVVECIKIIL | DLISESPIKG | RAQPYDPNFY | DETYDYGGFT | MMFDDRRGRP | 
    300:
    VGFPMRGRGG | FDRMPPGRGG | RPMPPSRRDY | DDMSPRRGPP | PPPPGRGGRG | 
    350:
    GSRARNLPLP | PPPPPRGGDL | MAYDRRGRPG | DRYDGMVGFS | ADETWDSAID | 
    400:
    TWSPSEWQMA | YEPQGGSGYD | YSYAGGRGSY | GDLGGPIITT | QVTIPKDLAG | 
    450:
    SIIGKGGQRI | KQIRHESGAS | IKIDEPLEGS | EDRIITITGT | QDQIQNAQYL | 
    463:
    LQNSVKQYSG | KFF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse hnRNP K
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    E0351h
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    ELISA Kit for Mouse hnRNP K
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    E0351m
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    ELISA Kit for Mouse hnRNP K
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    E0351r
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    ELISA Kit for Mouse hnRNP K
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    ELISA Kit for Mouse hnRNP K
    Cat.:
    E0351b
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    96T
    ELISA Kit for Mouse hnRNP K
    Cat.:
    E0351c
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    Packing:
    96T
    CLIA Kit for Mouse hnRNP K
    Cat.:
    U0351r
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    96T
    CLIA Kit for Mouse hnRNP K
    Cat.:
    U0351c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse hnRNP K
    Cat.:
    U0351b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse hnRNP K
    Cat.:
    U0351m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse hnRNP K
    Cat.:
    U0351h
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Mouse hnRNP K
    MSDS:
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    Polyclonal Antibody for Mouse hnRNP K
    Cat.:
    P0351Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse hnRNP K
    Cat.:
    P0351Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse hnRNP K
    Polyclonal Antibody for Mouse hnRNP K
    Polyclonal Antibody for Mouse hnRNP K
    Cat.:
    P0351Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse hnRNP K
    Monoclonal Antibody for Mouse hnRNP K
    Monoclonal Antibody for Mouse hnRNP K
    Monoclonal Antibody for Mouse hnRNP K
    Monoclonal Antibody for Mouse hnRNP K
    Monoclonal Antibody for Mouse hnRNP K
    Monoclonal Antibody for Mouse hnRNP K
    Protein for Mouse hnRNP K
    Protein for Mouse hnRNP K
    Protein for Mouse hnRNP K
    Protein for Mouse hnRNP K
    Protein for Mouse hnRNP K
    Protein for Mouse hnRNP K

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    References
    1. 1.
      "Purification, cloning, and expression of a murine phosphoprotein that binds the kappa B motif in vitro identifies it as the homolog of the human heterogeneous nuclear ribonucleoprotein K protein. Description of a novel DNA-dependent phosphorylation process."
      Ostrowski J. , van Seuningen I. , Seger R. , Rauch C.T. , Sleath P.R. , McMullen B.A. , Bomsztyk K.
      J. Biol. Chem.269:17626-17634(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);PARTIAL PROTEIN SEQUENCE
      tissue: Lymphoma.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Spinal ganglion.
      tissue: Testis.
      tissue: Thymus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      Lubec G. , Klug S. , Yang J.W. , Zigmond M.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 149-163 AND 207-219;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Hippocampus.
    5. 5.
      "Zik1, a transcriptional repressor that interacts with the heterogeneous nuclear ribonucleoprotein particle K protein."
      Denisenko O.N. , O'Neill B. , Ostrowski J. , Van Seuningen I. , Bomsztyk K.
      J. Biol. Chem.271:27701-27706(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZIK1
    6. 6.
      "hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage."
      Moumen A. , Masterson P. , O'Connor M.J. , Jackson S.P.
      Cell123:1065-1078(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    7. 7.
      "A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response."
      Huarte M. , Guttman M. , Feldser D. , Garber M. , Koziol M.J. , Kenzelmann-Broz D. , Khalil A.M. , Zuk O. , Amit I. , Rabani M. , Attardi L.D. , Regev A. , Lander E.S. , Jacks T. , Rinn J.L.
      Cell142:409-419(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatids."
      Berkovits B.D. , Wang L. , Guarnieri P. , Wolgemuth D.J.
      Nucleic Acids Res.40:7162-7175(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BRDT
    9. 9.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-198;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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