Gene name:
Hsp90aa1 (Hsp86;Hsp86-1;Hspca) ;
Protein name:
Heat shock protein HSP 90-alpha ;
Alternative:
Tumor-specific transplantation 86 kDa antigen (TSTA) ;Heat shock 86 kDa (HSP 86;HSP86) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer. Interacts with AHSA1, FNIP1, HSF1, SMYD3 and TOM34 (By similarity). Interacts with TERT; the interaction, together with PTGES3, is required for correct assembly and stabilization of the TERT holoenzyme complex (By similarity). Interacts with CHORDC1 and DNAJC7.
Function:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Subcellular Location:
Cytoplasm
Melanosome
Protein Attributes:
50:
MPEETQTQDQ | PMEEEEVETF | AFQAEIAQLM | SLIINTFYSN | KEIFLRELIS |
100:
NSSDALDKIR | YESLTDPSKL | DSGKELHINL | IPSKQDRTLT | IVDTGIGMTK |
150:
ADLINNLGTI | AKSGTKAFME | ALQAGADISM | IGQFGVGFYS | AYLVAEKVTV |
200:
ITKHNDDEQY | AWESSAGGSF | TVRTDTGEPM | GRGTKVILHL | KEDQTEYLEE |
250:
RRIKEIVKKH | SQFIGYPITL | FVEKERDKEV | SDDEAEEKEE | KEEEKEKEEK |
300:
ESDDKPEIED | VGSDEEEEEK | KDGDKKKKKK | IKEKYIDQEE | LNKTKPIWTR |
350:
NPDDITNEEY | GEFYKSLTND | WEEHLAVKHF | SVEGQLEFRA | LLFVPRRAPF |
400:
DLFENRKKKN | NIKLYVRRVF | IMDNCEELIP | EYLNFIRGVV | DSEDLPLNIS |
450:
REMLQQSKIL | KVIRKNLVKK | CLELFTELAE | DKENYKKFYE | QFSKNIKLGI |
500:
HEDSQNRKKL | SELLRYYTSA | SGDEMVSLKD | YCTRMKENQK | HIYFITGETK |
550:
DQVANSAFVE | RLRKHGLEVI | YMIEPIDEYC | VQQLKEFEGK | TLVSVTKEGL |
600:
ELPEDEEEKK | KQEEKKTKFE | NLCKIMKDIL | EKKVEKVVVS | NRLVTSPCCI |
650:
VTSTYGWTAN | MERIMKAQAL | RDNSTMGYMA | AKKHLEINPD | HSIIETLRQK |
700:
AEADKNDKSV | KDLVILLYET | ALLSSGFSLE | DPQTHANRIY | RMIKLGLGID |
733:
EDDPTVDDTS | AAVTEEMPPL | EGDDDTSRME | EVD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Rat
Mouse
Pig
Rabbit
Chicken
ELISA Kit for Mouse Heat shock protein HSP 90-alpha
ELISA Kit for Mouse Heat shock protein HSP 90-alpha
ELISA Kit for Mouse Heat shock protein HSP 90-alpha
ELISA Kit for Mouse Heat shock protein HSP 90-alpha
ELISA Kit for Mouse Heat shock protein HSP 90-alpha
ELISA Kit for Mouse Heat shock protein HSP 90-alpha
ELISA Kit for Mouse Heat shock protein HSP 90-alpha
CLIA Kit for Mouse Heat shock protein HSP 90-alpha
CLIA Kit for Mouse Heat shock protein HSP 90-alpha
CLIA Kit for Mouse Heat shock protein HSP 90-alpha
CLIA Kit for Mouse Heat shock protein HSP 90-alpha
CLIA Kit for Mouse Heat shock protein HSP 90-alpha
CLIA Kit for Mouse Heat shock protein HSP 90-alpha
CLIA Kit for Mouse Heat shock protein HSP 90-alpha
Polyclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Polyclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Polyclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Polyclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Polyclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Polyclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Polyclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Monoclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Monoclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Monoclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Monoclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Monoclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Monoclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Monoclonal Antibody for Mouse Heat shock protein HSP 90-alpha
Protein for Mouse Heat shock protein HSP 90-alpha
Protein for Mouse Heat shock protein HSP 90-alpha
Protein for Mouse Heat shock protein HSP 90-alpha
Protein for Mouse Heat shock protein HSP 90-alpha
Protein for Mouse Heat shock protein HSP 90-alpha
Protein for Mouse Heat shock protein HSP 90-alpha
Protein for Mouse Heat shock protein HSP 90-alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
BALB/c .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Retina .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-31
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-12;HOMODIMERIZATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 6-356
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 47-58; 61-69; 75-84; 88-112; 154-173; 186-201; 210-224; 285-356; 369-401; 448-457; 491-511; 515-535; 548-561; 569-574; 593-632 AND 634-648
strain :
C57BL/6 .
strain :
OF1 .
tissue :
Brain .
tissue :
Hippocampus .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 460-733
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN A COMPLEX WITH NR3C1 AND FKBP4; PPID; PPP5C OR STIP1
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN A COMPLEX WITH NR3C1 AND FKBP4
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN A HETEROMULTIMERIC COMPLEX WITH NR3C1 AND FKBP4 OR FKBP5;SUBCELLULAR LOCATION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT THR-5 AND THR-7 BY PRKDC
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ISGYLATION
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-493;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Mast cell .
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-263;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-314;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-263;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-263;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
19.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
,
Chen Y.
,
Tishkoff D.X.
,
Peng C.
,
Tan M.
,
Dai L.
,
Xie Z.
,
Zhang Y.
,
Zwaans B.M.
,
Skinner M.E.
,
Lombard D.B.
,
Zhao Y.
Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-58 AND LYS-84;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .