HSF4 ELISA Kit for Human(Homo sapiens) | EIAab.comHSF4 ELISA Kit for Human(Homo sapiens)

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HSF4 (Gene name),

Heat shock factor protein 4 (Protein name ), HSF4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HSF4;

Protein name:

Heat shock factor protein 4(HSF 4;hHSF4);

Alternative:

Heat shock transcription factor 4(HSTF 4);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotrimer. Exhibits constitutive DNA binding and forms trimers even in the absence of stress. Interacts with DUSP26, MAPK1, MAPK2 and MAP kinase p38.

Function:

DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

492

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

492:

LLLDVQAALG | GPALGLPGAL | TIYSTPESRT | ASYLGPEASP | SP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9ULV5

Pfam:

PF00447

UniGene:

Hs.512156

String:

Q9ULV5

KEGG:

hsa:3299

MIM:

116800

STRING:

9606.ENSP00000264009

Uniprot:

Q9ULV5

FOR

ELISA Kit for Human HSF 4

Cat.:

E9000m

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MSDS:

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Packing:

96T

ELISA Kit for Human HSF 4

Cat.:

E9000h

Price:

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Manual:

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Packing:

96T

Range:

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ELISA Kit for Human HSF 4

MSDS:

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CLIA Kit for Human HSF 4

MSDS:

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CLIA Kit for Human HSF 4

Cat.:

U9000m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human HSF 4

Cat.:

U9000h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human HSF 4

Cat.:

P9000Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human HSF 4

Cat.:

P9000Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human HSF 4

Protein for Human HSF 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator."
Nakai A. , Tanabe M. , Kawazoe Y. , Inazawa J. , Morimoto R.I. , Nagata K.
Mol. Cell. Biol.17:469-481(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM HSF4A)
tissue: Heart.
2.

"The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing."
Tanabe M. , Sasai N. , Nagata K. , Liu X.-D. , Liu P.C.C. , Thiele D.J. , Nakai A.
J. Biol. Chem.274:27845-27856(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM HSF4B);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-396 (ISOFORM HSF4A);ALTERNATIVE SPLICING;CHARACTERIZATION
3.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Association and regulation of heat shock transcription factor 4b with both extracellular signal-regulated kinase mitogen-activated protein kinase and dual-specificity tyrosine phosphatase DUSP26."
Hu Y. , Mivechi N.F.
Mol. Cell. Biol.26:3282-3294(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DUSP26; MAPK1; MAPK2 AND MAP KINASE P38;PTM
5.

"PDSM, a motif for phosphorylation-dependent SUMO modification."
Hietakangas V. , Anckar J. , Blomster H.A. , Fujimoto M. , Palvimo J.J. , Nakai A. , Sistonen L.
Proc. Natl. Acad. Sci. U.S.A.103:45-50(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-293;PHOSPHORYLATION AT SER-298;FUNCTION;MUTAGENESIS OF LYS-293 AND SER-298
6.

"Human ALKBH4 interacts with proteins associated with transcription."
Bjornstad L.G. , Meza T.J. , Otterlei M. , Olafsrud S.M. , Meza-Zepeda L.A. , Falnes P.O.
PLoS ONE7:E49045-E49045(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALKBH4
7.

"Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract."
Bu L. , Jin Y. , Shi Y. , Chu R. , Ban A. , Eiberg H. , Andres L. , Jiang H. , Zheng G. , Qian M. , Cui B. , Xia Y. , Liu J. , Hu L. , Zhao G. , Hayden M.R. , Kong X.
Nat. Genet.31:276-278(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CTRCT5 ASP-19; VAL-86; PRO-114 AND CYS-119;TISSUE SPECIFICITY
8.

"Novel HSF4 mutation causes congenital total white cataract in a Chinese family."
Ke T. , Wang Q.K. , Ji B. , Wang X. , Liu P. , Zhang X. , Tang Z. , Ren X. , Liu M.
Am. J. Ophthalmol.142:298-303(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CTRCT5 HIS-73

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