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Index > Protein center > HSPA2(Gene name) > Human
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  • HSPA2 (Gene name),
  • Heat shock-related 70 kDa protein 2 (Protein name ),  HSP72_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    HSPA2;
    Protein name:
    Heat shock-related 70 kDa protein 2(Heat shock 70 kDa protein 2);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with ZNF541.
    Function:
    In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    639
    Sequence:
    50:
    MSARGPAIGI | DLGTTYSCVG | VFQHGKVEII | ANDQGNRTTP | SYVAFTDTER | 
    100:
    LIGDAAKNQV | AMNPTNTIFD | AKRLIGRKFE | DATVQSDMKH | WPFRVVSEGG | 
    150:
    KPKVQVEYKG | ETKTFFPEEI | SSMVLTKMKE | IAEAYLGGKV | HSAVITVPAY | 
    200:
    FNDSQRQATK | DAGTITGLNV | LRIINEPTAA | AIAYGLDKKG | CAGGEKNVLI | 
    250:
    FDLGGGTFDV | SILTIEDGIF | EVKSTAGDTH | LGGEDFDNRM | VSHLAEEFKR | 
    300:
    KHKKDIGPNK | RAVRRLRTAC | ERAKRTLSSS | TQASIEIDSL | YEGVDFYTSI | 
    350:
    TRARFEELNA | DLFRGTLEPV | EKALRDAKLD | KGQIQEIVLV | GGSTRIPKIQ | 
    400:
    KLLQDFFNGK | ELNKSINPDE | AVAYGAAVQA | AILIGDKSEN | VQDLLLLDVT | 
    450:
    PLSLGIETAG | GVMTPLIKRN | TTIPTKQTQT | FTTYSDNQSS | VLVQVYEGER | 
    500:
    AMTKDNNLLG | KFDLTGIPPA | PRGVPQIEVT | FDIDANGILN | VTAADKSTGK | 
    550:
    ENKITITNDK | GRLSKDDIDR | MVQEAERYKS | EDEANRDRVA | AKNALESYTY | 
    600:
    NIKQTVEDEK | LRGKISEQDK | NKILDKCQEV | INWLDRNQMA | EKDEYEHKQK | 
    639:
    ELERVCNPII | SKLYQGGPGG | GSGGGGSGAS | GGPTIEEVD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    MIM:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    E9985h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    E9985m
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    ELISA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    E9985r
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    Packing:
    96T
    ELISA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    E9985b
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    Packing:
    96T
    CLIA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    U9985r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    U9985b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    U9985h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Heat shock 70 kDa protein 2
    Cat.:
    U9985m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Heat shock 70 kDa protein 2
    Polyclonal Antibody for Human Heat shock 70 kDa protein 2
    Cat.:
    P9985Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Heat shock 70 kDa protein 2
    Cat.:
    P9985Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Heat shock 70 kDa protein 2
    Monoclonal Antibody for Human Heat shock 70 kDa protein 2
    Monoclonal Antibody for Human Heat shock 70 kDa protein 2
    Monoclonal Antibody for Human Heat shock 70 kDa protein 2
    Monoclonal Antibody for Human Heat shock 70 kDa protein 2
    Protein for Human Heat shock 70 kDa protein 2
    Protein for Human Heat shock 70 kDa protein 2
    Protein for Human Heat shock 70 kDa protein 2
    Protein for Human Heat shock 70 kDa protein 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning, sequencing, and mapping of the human chromosome 14 heat shock protein gene (HSPA2)."
      Bonnycastle L.L.C. , Yu C.-E. , Hunt C.R. , Trask B.J. , Clancy K.P. , Weber J.L. , Patterson D. , Schellenberg G.D.
      Genomics23:85-93(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      Goralski T.J. , Krensky A.M.
      Submitted (1996-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      NIEHS SNPs program
      Submitted (2006-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-191 AND GLU-496
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Eye.
    6. 6.
      "A heat shock gene at 14q22: mapping and expression."
      Roux A.-F. , Nguyen V.T.T. , Squire J.A. , Cox D.W.
      Hum. Mol. Genet.3:1819-1822(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-126
    7. 7.
      "FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes."
      Jarczowski F. , Fischer G. , Edlich F.
      Biochemistry47:6946-6952(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FKBP6
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Identification and characterization of a novel human methyltransferase modulating Hsp70 function through lysine methylation."
      Jakobsson M.E. , Moen A. , Bousset L. , Egge-Jacobsen W. , Kernstock S. , Melki R. , Falnes P.O.
      J. Biol. Chem.288:27752-27763(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION AT LYS-564;MUTAGENESIS OF LYS-564
    10. 10.
      "Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78."
      Wisniewska M. , Karlberg T. , Lehtio L. , Johansson I. , Kotenyova T. , Moche M. , Schuler H.
      PLoS ONE5:E8625-E8625(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS) OF 6-386 IN COMPLEX WITH ADP AND PHOSPHATE
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