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Index > Protein center > HTRA2(Gene name) > Bovine
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  • HTRA2 (Gene name),
  • Serine protease HTRA2, mitochondrial (Protein name ),  HTRA2_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    HTRA2;
    Protein name:
    Serine protease HTRA2, mitochondrial;
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homotrimer. Interacts with MXI2. Interacts with THAP5 under apoptotic conditions (By similarity). The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP.
    Function:
    Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis.
    Subcellular Location:
    Mitochondrion intermembrane space Mitochondrion membrane Single-pass membrane protein Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.
    Protein Attributes:
    Sequence length:
    458
    Sequence:
    50:
    MAALRAGRGA | GWSLRGWRAL | WGGRWGKGPL | LTPDLRALLT | SGTPDPRTRV | 
    100:
    TYGTPSFRAR | LSVGVPEPRT | CLRSRTSDLR | ARLIAGTPDP | RTPEDSGTPG | 
    150:
    TRLRVWLAVA | LGAGGAVLLL | FWGGGRGPPA | VLASVLGSPP | TSPRSQYNFI | 
    200:
    ADVVEKTAPA | VVYIEILGRH | PFSGREVPIS | NGSGFVVAAD | GLIVTNAHVV | 
    250:
    ADRRRVRVRL | PSGDTYEAVV | TAVDPVADIA | TLRIQTKEPL | PTLPLGRSAD | 
    300:
    VRQGEFVVAM | GSPFALQNTI | TSGIVSSAQR | PAKDLGLPQT | NVEYIQTDAA | 
    350:
    IDFGNSGGPL | VNLDGEVIGV | NTMKVTSGIS | FAIPSDRLRE | FLHRGEKKNS | 
    400:
    WFGISGSQRR | YIGVMMLTLT | PSILAELQLR | EPSFPDVQHG | VLIHKVILDS | 
    450:
    PAHRAGLRPG | DVILAIGEQL | VQNAEDIYEA | VRTQSQLAVR | IRRGQETLTL | 
    458:
    YVTPEVTE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    E15152h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    E15152m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    E15152b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    U15152h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    U15152m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    U15152b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    P15152Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Serine protease HTRA2, mitochondrial
    Cat.:
    P15152Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Serine protease HTRA2, mitochondrial
    Monoclonal Antibody for Bovine Serine protease HTRA2, mitochondrial
    Monoclonal Antibody for Bovine Serine protease HTRA2, mitochondrial
    Monoclonal Antibody for Bovine Serine protease HTRA2, mitochondrial
    Protein for Bovine Serine protease HTRA2, mitochondrial
    Protein for Bovine Serine protease HTRA2, mitochondrial
    Protein for Bovine Serine protease HTRA2, mitochondrial

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Basal ganglia.
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