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Index > Protein center > Gck(Gene name) > Rat
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  • Gck (Gene name),
  • Glucokinase (Protein name ),  HXK4_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Gck;
    Protein name:
    Glucokinase;
    Alternative:
    Hexokinase-4(HK4);Hexokinase type IV(HK IV);Hexokinase-D;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    465
    Sequence:
    50:
    MLDDRARMEA | TKKEKVEQIL | AEFQLQEEDL | KKVMSRMQKE | MDRGLRLETH | 
    100:
    EEASVKMLPT | YVRSTPEGSE | VGDFLSLDLG | GTNFRVMLVK | VGEGEAGQWS | 
    150:
    VKTKHQMYSI | PEDAMTGTAE | MLFDYISECI | SDFLDKHQMK | HKKLPLGFTF | 
    200:
    SFPVRHEDLD | KGILLNWTKG | FKASGAEGNN | IVGLLRDAIK | RRGDFEMDVV | 
    250:
    AMVNDTVATM | ISCYYEDRQC | EVGMIVGTGC | NACYMEEMQN | VELVEGDEGR | 
    300:
    MCVNTEWGAF | GDSGELDEFL | LEYDRMVDES | SANPGQQLYE | KIIGGKYMGE | 
    350:
    LVRLVLLKLV | DENLLFHGEA | SEQLRTRGAF | ETRFVSQVES | DSGDRKQIHN | 
    400:
    ILSTLGLRPS | VTDCDIVRRA | CESVSTRAAH | MCSAGLAGVI | NRMRESRSED | 
    450:
    VMRITVGVDG | SVYKLHPSFK | ERFHASVRRL | TPNCEITFIE | SEEGSGRGAA | 
    465:
    LVSAVACKKA | CMLAQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Glucokinase
    Cat.:
    E0667h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Glucokinase
    Cat.:
    E0667r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Glucokinase
    Cat.:
    E0667m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Glucokinase
    Cat.:
    U0667m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Glucokinase
    Cat.:
    U0667h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Glucokinase
    Cat.:
    U0667r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat Glucokinase
    Cat.:
    P0667Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Glucokinase
    Cat.:
    P0667Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Glucokinase
    Cat.:
    P0667Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Glucokinase
    Monoclonal Antibody for Rat Glucokinase
    Monoclonal Antibody for Rat Glucokinase
    Protein for Rat Glucokinase
    Protein for Rat Glucokinase
    Protein for Rat Glucokinase

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The amino acid sequence of rat liver glucokinase deduced from cloned cDNA."
      Andreone T.L. , Printz R.L. , Pilkis S.J. , Magnuson M.A. , Granner D.K.
      J. Biol. Chem.264:363-369(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);PARTIAL PROTEIN SEQUENCE
      tissue: Liver.
    2. 2.
      "Alternative splicing of glucokinase mRNA in rat liver."
      Hayzer D.J. , Iynedjian P.B.
      Biochem. J.270:261-263(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];ALTERNATIVE SPLICING
      tissue: Liver.
    3. 3.
      "An alternate promoter in the glucokinase gene is active in the pancreatic beta cell."
      Magnuson M.A. , Shelton K.D.
      J. Biol. Chem.264:15936-15942(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 1-15 (ISOFORM 1)
      tissue: Pancreas.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15 (ISOFORM 3)
    5. 5.
      "Characterization of the 5' flanking region of rat glucokinase gene."
      Noguchi T. , Takenaka M. , Yamada K. , Matsuda T. , Hashimoto M. , Tanaka T.
      Biochem. Biophys. Res. Commun.164:1247-1252(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-15 (ISOFORM 3)
    6. 6.
      "Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells."
      Hughes S.D. , Quaade C. , Milburn J.L. , Cassidy L. , Newgard C.B.
      J. Biol. Chem.266:4521-4530(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-166 (ISOFORM 1)
    7. 7.
      "Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase."
      de la Iglesia N. , Veiga-da-Cunha M. , Van Schaftingen E. , Guinovart J.J. , Ferrer J.C.
      FEBS Lett.456:332-338(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;SUBCELLULAR LOCATION
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