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Index > Protein center > HAS1(Gene name) > Human
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  • HAS1 (Gene name),
  • Hyaluronan synthase 1 (Protein name ),  HYAS1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HAS1(HAS);
    Protein name:
    Hyaluronan synthase 1;
    Alternative:
    Hyaluronic acid synthase 1(HA synthase 1);Hyaluronate synthase 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    578
    Sequence:
    50:
    MRQQDAPKPT | PAACRCSGLA | RRVLTIAFAL | LILGLMTWAY | AAGVPLASDR | 
    100:
    YGLLAFGLYG | AFLSAHLVAQ | SLFAYLEHRR | VAAAARGPLD | AATARSVALT | 
    150:
    ISAYQEDPAY | LRQCLASARA | LLYPRARLRV | LMVVDGNRAE | DLYMVDMFRE | 
    200:
    VFADEDPATY | VWDGNYHQPW | EPAAAGAVGA | GAYREVEAED | PGRLAVEALV | 
    250:
    RTRRCVCVAQ | RWGGKREVMY | TAFKALGDSV | DYVQVCDSDT | RLDPMALLEL | 
    300:
    VRVLDEDPRV | GAVGGDVRIL | NPLDSWVSFL | SSLRYWVAFN | VERACQSYFH | 
    350:
    CVSCISGPLG | LYRNNLLQQF | LEAWYNQKFL | GTHCTFGDDR | HLTNRMLSMG | 
    400:
    YATKYTSRSR | CYSETPSSFL | RWLSQQTRWS | KSYFREWLYN | ALWWHRHHAW | 
    450:
    MTYEAVVSGL | FPFFVAATVL | RLFYAGRPWA | LLWVLLCVQG | VALAKAAFAA | 
    500:
    WLRGCLRMVL | LSLYAPLYMC | GLLPAKFLAL | VTMNQSGWGT | SGRRKLAANY | 
    550:
    VPLLPLALWA | LLLLGGLVRS | VAHEARADWS | GPSRAAEAYH | LAAGAGAYVG | 
    578:
    YWVAMLTLYW | VGVRRLCRRR | TGGYRVQV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Hyaluronan synthase 1
    Cat.:
    E9712h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hyaluronan synthase 1
    Cat.:
    E9712m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hyaluronan synthase 1
    Cat.:
    U9712h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hyaluronan synthase 1
    Cat.:
    U9712m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Hyaluronan synthase 1
    Cat.:
    P9712Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hyaluronan synthase 1
    Cat.:
    P9712Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Hyaluronan synthase 1
    Monoclonal Antibody for Human Hyaluronan synthase 1
    Protein for Human Hyaluronan synthase 1
    Protein for Human Hyaluronan synthase 1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning of human hyaluronan synthase."
      Itano N. , Kimata K.
      Biochem. Biophys. Res. Commun.222:816-820(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-14;TISSUE SPECIFICITY
      tissue: Fetal brain.
    2. 2.
      "Functional cloning of the cDNA for a human hyaluronan synthase."
      Shyjan A.M. , Heldin P. , Butcher E.C. , Yoshino T. , Briskin M.J.
      J. Biol. Chem.271:23395-23399(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-14
      tissue: Lymph node.
    3. 3.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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