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Index > Protein center > IDO1(Gene name) > Human
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  • IDO1 (Gene name),
  • Indoleamine 2,3-dioxygenase 1 (Protein name ),  I23O1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IDO1(IDO;INDO);
    Protein name:
    Indoleamine 2,3-dioxygenase 1(IDO-1);
    Alternative:
    Indoleamine-pyrrole 2,3-dioxygenase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.
    Subcellular Location:
    Protein Attributes:
    Sequence length:
    403
    Sequence:
    50:
    MAHAMENSWT | ISKEYHIDEE | VGFALPNPQE | NLPDFYNDWM | FIAKHLPDLI | 
    100:
    ESGQLRERVE | KLNMLSIDHL | TDHKSQRLAR | LVLGCITMAY | VWGKGHGDVR | 
    150:
    KVLPRNIAVP | YCQLSKKLEL | PPILVYADCV | LANWKKKDPN | KPLTYENMDV | 
    200:
    LFSFRDGDCS | KGFFLVSLLV | EIAAASAIKV | IPTVFKAMQM | QERDTLLKAL | 
    250:
    LEIASCLEKA | LQVFHQIHDH | VNPKAFFSVL | RIYLSGWKGN | PQLSDGLVYE | 
    300:
    GFWEDPKEFA | GGSAGQSSVF | QCFDVLLGIQ | QTAGGGHAAQ | FLQDMRRYMP | 
    350:
    PAHRNFLCSL | ESNPSVREFV | LSKGDAGLRE | AYDACVKALV | SLRSYHLQIV | 
    400:
    TKYILIPASQ | QPKENKTSED | PSKLEAKGTG | GTDLMNFLKT | VRSTTEKSLL | 
    403:
    KEG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    KEGG:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human IDO-1
    Cat.:
    E1547h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IDO-1
    Cat.:
    E1547m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IDO-1
    Cat.:
    E1547r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IDO-1
    Cat.:
    U1547r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IDO-1
    Cat.:
    U1547h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IDO-1
    Cat.:
    U1547m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human IDO-1
    Cat.:
    P1547Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IDO-1
    Cat.:
    P1547Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IDO-1
    Cat.:
    P1547Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human IDO-1
    Monoclonal Antibody for Human IDO-1
    Monoclonal Antibody for Human IDO-1
    Protein for Human IDO-1
    Protein for Human IDO-1
    Protein for Human IDO-1

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    Linearity
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    References
    1. 1.
      "Molecular cloning, sequencing and expression of human interferon-gamma-inducible indoleamine 2,3-dioxygenase cDNA."
      Dai W. , Gupta S.L.
      Biochem. Biophys. Res. Commun.168:1-8(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION BY IFNG
      tissue: Fibroblast.
    2. 2.
      "Primary structure of human indoleamine 2,3-dioxygenase deduced from the nucleotide sequence of its cDNA."
      Tone S. , Takikawa O. , Habara-Ohkubo A. , Kadoya A. , Yoshida R. , Kido R.
      Nucleic Acids Res.18:367-367(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      tissue: Lung.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Human indoleamine 2,3-dioxygenase from peripheral blood."
      He X. , Xu L. , Liu Y. , Zeng Y.
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Peripheral blood.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    7. 7.
      "Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan."
      Metz R. , Duhadaway J.B. , Kamasani U. , Laury-Kleintop L. , Muller A.J. , Prendergast G.C.
      Cancer Res.67:7082-7087(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ENZYME REGULATION;CATALYTIC ACTIVITY
    8. 8.
      "Evolution of vertebrate indoleamine 2,3-dioxygenases."
      Yuasa H.J. , Takubo M. , Takahashi A. , Hasegawa T. , Noma H. , Suzuki T.
      J. Mol. Evol.65:705-714(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOPHYSICOCHEMICAL PROPERTIES
    9. 9.
      "Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase."
      Sugimoto H. , Oda S. , Otsuki T. , Hino T. , Yoshida T. , Shiro Y.
      Proc. Natl. Acad. Sci. U.S.A.103:2611-2616(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS)
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