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Index > Protein center > IGFBP6(Gene name) > Human
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  • IGFBP6 (Gene name),
  • Insulin-like growth factor-binding protein 6 (Protein name ),  IBP6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IGFBP6(IBP6);
    Protein name:
    Insulin-like growth factor-binding protein 6(IBP-6;IGF-binding protein 6;IGFBP-6);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    240
    Sequence:
    50:
    MTPHRLLPPL | LLLLALLLAA | SPGGALARCP | GCGQGVQAGC | PGGCVEEEDG | 
    100:
    GSPAEGCAEA | EGCLRREGQE | CGVYTPNCAP | GLQCHPPKDD | EAPLRALLLG | 
    150:
    RGRCLPARAP | AVAEENPKES | KPQAGTARPQ | DVNRRDQQRN | PGTSTTPSQP | 
    200:
    NSAGVQDTEM | GPCRRHLDSV | LQQLQTEVYR | GAQTLYVPNC | DHRGFYRKRQ | 
    240:
    CRSSQGQRRG | PCWCVDRMGK | SLPGSPDGNG | SSSCPTGSSG | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    Pfam:
    SMR:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human IBP-6
    Cat.:
    E0274h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IBP-6
    Cat.:
    E0274r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IBP-6
    Cat.:
    E0274m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human IBP-6
    Cat.:
    E0274b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-6
    Cat.:
    U0274h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-6
    Cat.:
    U0274r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-6
    Cat.:
    U0274b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human IBP-6
    Cat.:
    U0274m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human IBP-6
    Cat.:
    P0274Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IBP-6
    Polyclonal Antibody for Human IBP-6
    Cat.:
    P0274Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IBP-6
    Cat.:
    P0274Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human IBP-6
    Monoclonal Antibody for Human IBP-6
    Monoclonal Antibody for Human IBP-6
    Monoclonal Antibody for Human IBP-6
    Protein for Human IBP-6
    Protein for Human IBP-6
    Protein for Human IBP-6
    Protein for Human IBP-6

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    Precision
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    Linearity
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    References
    1. 1.
      "Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum."
      Kiefer M.C. , Masiarz F.R. , Bauer D.M. , Zapf J.
      J. Biol. Chem.266:9043-9049(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Osteosarcoma.
    2. 2.
      "Characterization and chromosomal localization of the human insulin-like growth factor-binding protein 6 gene."
      Ehrenborg E. , Zazzi H. , Lagercrantz S. , Granqvist M. , Hillerbrand U. , Allander S.V. , Larsson C. , Luthman H.
      Mamm. Genome10:376-380(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      NIEHS SNPs program
      Submitted (2003-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLY-128 AND GLN-217
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
    5. 5.
      "Isolation and molecular cloning of insulin-like growth factor-binding protein-6."
      Shimasaki S. , Gao L. , Shimonaka M. , Ling N.
      Mol. Endocrinol.5:938-948(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-240
      tissue: Placenta.
    6. 6.
      "Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia."
      Zapf J. , Kiefer M. , Merryweather J. , Musiarz F. , Bauer D. , Born W. , Fischer J.A. , Froesch E.R.
      J. Biol. Chem.265:14892-14898(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-57
      tissue: Serum.
    7. 7.
      "Isolation from human cerebrospinal fluid of a new insulin-like growth factor-binding protein with a selective affinity for IGF-II."
      Roghani M. , Hossenlopp P. , Lepage P. , Balland A. , Binoux M.
      FEBS Lett.255:253-258(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PROTEIN SEQUENCE OF 28-42
      tissue: Cerebrospinal fluid.
    8. 8.
      "Purification and properties of a novel insulin-like growth factor-II binding protein from transformed human fibroblasts."
      Martin J.L. , Willetts K.E. , Baxter R.C.
      J. Biol. Chem.265:4124-4130(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-42
      tissue: Fibroblast.
    9. 9.
      "A novel human insulin-like growth factor binding protein secreted by osteoblast-like cells."
      Andress D.L. , Birnbaum R.S.
      Biochem. Biophys. Res. Commun.176:213-218(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-42
      tissue: Osteosarcoma.
    10. 10.
      "Identification of O-glycosylation sites and partial characterization of carbohydrate structure and disulfide linkages of human insulin-like growth factor binding protein 6."
      Neumann G.M. , Marinaro J.A. , Bach L.A.
      Biochemistry37:6572-6585(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-126; SER-144; THR-145; THR-146 AND SER-152
    11. 11.
      "The N-terminal disulfide linkages of human insulin-like growth factor-binding protein-6 (hIGFBP-6) and hIGFBP-1 are different as determined by mass spectrometry."
      Neumann G.M. , Bach L.A.
      J. Biol. Chem.274:14587-14594(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS
    12. 12.
      "Enrichment of glycopeptides for glycan structure and attachment site identification."
      Nilsson J. , Rueetschi U. , Halim A. , Hesse C. , Carlsohn E. , Brinkmalm G. , Larson G.
      Nat. Methods6:809-811(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT THR-126;STRUCTURE OF CARBOHYDRATES
      tissue: Cerebrospinal fluid.
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