Gene name:
Icam1 (Icam-1) ;
Protein name:
Intercellular adhesion molecule 1 (ICAM-1) ;
Alternative:
MyD10 ;MALA-2 ;
CD:
CD54 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer. Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF.
Function:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MASTRAKPTL | PLLLALVTVV | IPGPGDAQVS | IHPREAFLPQ | GGSVQVNCSS |
100:
SCKEDLSLGL | ETQWLKDELE | SGPNWKLFEL | SEIGEDSSPL | CFENCGTVQS |
150:
SASATITVYS | FPESVELRPL | PAWQQVGKDL | TLRCHVDGGA | PRTQLSAVLL |
200:
RGEEILSRQP | VGGHPKDPKE | ITFTVLASRG | DHGANFSCRT | ELDLRPQGLA |
250:
LFSNVSEARS | LRTFDLPATI | PKLDTPDLLE | VGTQQKLFCS | LEGLFPASEA |
300:
RIYLELGGQM | PTQESTNSSD | SVSATALVEV | TEEFDRTLPL | RCVLELADQI |
350:
LETQRTLTVY | NFSAPVLTLS | QLEVSEGSQV | TVKCEAHSGS | KVVLLSGVEP |
400:
RPPTPQVQFT | LNASSEDHKR | SFFCSAALEV | AGKFLFKNQT | LELHVLYGPR |
450:
LDETDCLGNW | TWQEGSQQTL | KCQAWGNPSP | KMTCRRKADG | ALLPIGVVKS |
500:
VKQEMNGTYV | CHAFSSHGNV | TRNVYLTVLY | HSQNNWTIII | LVPVLLVIVG |
537:
LVMAASYVYN | RQRKIRIYKL | QKAQEEAIKL | KGQAPPP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Dog
Human
Bovine
ELISA Kit for Mouse ICAM-1
ELISA Kit for Mouse ICAM-1
ELISA Kit for Mouse ICAM-1
ELISA Kit for Mouse ICAM-1
ELISA Kit for Mouse ICAM-1
CLIA Kit for Mouse ICAM-1
CLIA Kit for Mouse ICAM-1
CLIA Kit for Mouse ICAM-1
CLIA Kit for Mouse ICAM-1
CLIA Kit for Mouse ICAM-1
Polyclonal Antibody for Mouse ICAM-1
Polyclonal Antibody for Mouse ICAM-1
Polyclonal Antibody for Mouse ICAM-1
Polyclonal Antibody for Mouse ICAM-1
Polyclonal Antibody for Mouse ICAM-1
Monoclonal Antibody for Mouse ICAM-1
Monoclonal Antibody for Mouse ICAM-1
Monoclonal Antibody for Mouse ICAM-1
Monoclonal Antibody for Mouse ICAM-1
Monoclonal Antibody for Mouse ICAM-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
strain :
BALB/c .
tissue :
Myeloma .
2.
Takei F.
Submitted (1990-04) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 X CBA .
tissue :
Thymus .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
NIH Swiss .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 4-131
7.
"N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry."
Otto V.I.
,
Damoc E.
,
Cueni L.N.
,
Schurpf T.
,
Frei R.
,
Ali S.
,
Callewaert N.
,
Moise A.
,
Leary J.A.
,
Folkers G.
,
Przybylski M.
Glycobiology16:1033-1044(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-47; ASN-185; ASN-204; ASN-267; ASN-311; ASN-362; ASN-388; ASN-409 AND ASN-456;ABSENCE OF GLYCOSYLATION AT ASN-469 AND ASN-485;IDENTIFICATION BY MASS SPECTROMETRY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-185; ASN-204; ASN-362; ASN-388; ASN-409 AND ASN-469