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Index > Protein center > ICAM2(Gene name) > Human
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  • ICAM2 (Gene name),
  • Intercellular adhesion molecule 2 (Protein name ),  ICAM2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ICAM2;
    Protein name:
    Intercellular adhesion molecule 2(ICAM-2);
    Alternative:

    CD:
    CD102;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    275
    Sequence:
    50:
    MSSFGYRTLT | VALFTLICCP | GSDEKVFEVH | VRPKKLAVEP | KGSLEVNCST | 
    100:
    TCNQPEVGGL | ETSLDKILLD | EQAQWKHYLV | SNISHDTVLQ | CHFTCSGKQE | 
    150:
    SMNSNVSVYQ | PPRQVILTLQ | PTLVAVGKSF | TIECRVPTVE | PLDSLTLFLF | 
    200:
    RGNETLHYET | FGKAAPAPQE | ATATFNSTAD | REDGHRNFSC | LAVLDLMSRG | 
    250:
    GNIFHKHSAP | KMLEIYEPVS | DSQMVIIVTV | VSVLLSLFVT | SVLLCFIFGQ | 
    275:
    HLRQQRMGTY | GVRAAWRRLP | QAFRP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    SMR:
    MIM:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human ICAM-2
    Cat.:
    E0534m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human ICAM-2
    Cat.:
    E0534h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human ICAM-2
    Cat.:
    U0534m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ICAM-2
    Cat.:
    U0534h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ICAM-2
    Cat.:
    P0534Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ICAM-2
    Cat.:
    P0534Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ICAM-2
    Monoclonal Antibody for Human ICAM-2
    Protein for Human ICAM-2
    Protein for Human ICAM-2

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1."
      Staunton D.E. , Dustin M.L. , Springer T.A.
      Nature339:61-64(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Endothelial cell.
    2. 2.
      "Structure of the gene for the human intercellular adhesion molecule 2 (ICAM-2)."
      Garcia-Aguilar J. , Staunton D. , Springer T.A.
      Submitted (1990-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      "Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini."
      Xu G. , Shin S.B. , Jaffrey S.R.
      Proc. Natl. Acad. Sci. U.S.A.106:19310-19315(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE [LARGE SCALE ANALYSIS] OF 25-33
      tissue: Leukemic T-cell.
    5. 5.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-105 AND ASN-176
      tissue: Plasma.
    6. 6.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-82; ASN-105; ASN-153 AND ASN-176
      tissue: Leukemic T-cell.
    7. 7.
      "Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface."
      Casasnovas J.M. , Springer T.A. , Liu J.-H. , Harrison S.C. , Wang J.-H.
      Nature387:312-315(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 25-216
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