Intercellular adhesion molecule 2 (Protein name
), ICAM2_HUMAN from NCBI database.
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Gene name:
ICAM2;
Protein name:
Intercellular adhesion molecule 2(ICAM-2);
Alternative:
CD:
CD102;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
N/A
Function:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
"Structure of the gene for the human intercellular adhesion molecule 2 (ICAM-2)." Garcia-Aguilar J.
,
Staunton D.
,
Springer T.A.
Submitted (1990-02) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
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Cited for: PROTEIN SEQUENCE [LARGE SCALE ANALYSIS] OF 25-33
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Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-105 AND ASN-176
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Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-82; ASN-105; ASN-153 AND ASN-176
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Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 25-216
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