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Index > Protein center > EIF2S3L(Gene name) > Human
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  • EIF2S3L (Gene name),
  • Eukaryotic translation initiation factor 2 subunit 3-like protein (Protein name ),  IF2GL_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    EIF2S3L;
    Protein name:
    Eukaryotic translation initiation factor 2 subunit 3-like protein;
    Alternative:
    Eukaryotic translation initiation factor 2 subunit gamma A(eIF-2-gamma A;eIF-2gA);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterotrimer composed of an alpha, a beta and a gamma chain.
    Function:
    eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    472
    Sequence:
    50:
    MAGGEAGVTL | GQPHLSRQDL | TTLDVTKLTP | LSHEVISRQA | TINIGTIGHV | 
    100:
    AHGKSTVVKA | ISGVHTVRFK | NELERNITIK | LGYANAKIYQ | LDDPSCPRPE | 
    150:
    CYRSCGSSMP | DEFPTDIPGT | KGNFRLVRHV | SFVDCPGHDI | LMATMLNGAA | 
    200:
    VMDAALLLIA | GNESCPQPQT | SEHLAAIEIM | KLKHILILQN | KIDLVKERQA | 
    250:
    KEQYEQILAF | VQGTVAEGAP | IIPISAQLKY | NIEVVCEYIV | KKIPVPPRDF | 
    300:
    TSEPRLIVIR | SFDVNKPGCE | VDDLKGGVAG | GSILKGVLKV | GQETEVRPGI | 
    350:
    VSKDSEGKLM | CKSIFSKIVS | LFAEHNDLQY | AAPGGLIGVG | TKIDPTLCRA | 
    400:
    DRMVGQILGA | VGALPEIFTE | LEISYFLLRR | LLGVRTEGDK | KAAKVQKLSK | 
    450:
    NEVLMVNIGS | LSTGGRVSAV | KADLGKIVLT | NPVCTEVGEK | IALSRRVEKH | 
    472:
    WRLIGWGQIR | RGVTIKPTVD | DD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Eukaryotic translation initiation factor 2 subunit 3-like protein
    CLIA Kit for Human Eukaryotic translation initiation factor 2 subunit 3-like protein
    Polyclonal Antibody for Human Eukaryotic translation initiation factor 2 subunit 3-like protein
    Monoclonal Antibody for Human Eukaryotic translation initiation factor 2 subunit 3-like protein
    Protein for Human Eukaryotic translation initiation factor 2 subunit 3-like protein

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Emergence of young human genes after a burst of retroposition in primates."
      Marques A.C. , Dupanloup I. , Vinckenbosch N. , Reymond A. , Kaessmann H.
      PLoS Biol.3:E357-E357(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];EVOLUTIONARY ANALYSIS
    2. 2.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-471 (ISOFORM 2)
      tissue: Testis.
    4. 4.
      "Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution."
      Ehrmann I.E. , Ellis P.S. , Mazeyrat S. , Duthie S. , Brockdorff N. , Mattei M.-G. , Gavin M.A. , Affara N.A. , Brown G.M. , Simpson E. , Mitchell M.J. , Scott D.M.
      Hum. Mol. Genet.7:1725-1737(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 61-309
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