Gene name:
EIF5B (IF2;KIAA0741) ;
Protein name:
Eukaryotic translation initiation factor 5B (eIF-5B) ;
Alternative:
Translation initiation factor IF-2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with ANXA5 in a calcium and phospholipid-dependent manner.
Function:
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MGKKQKNKSE | DSTKDDIDLD | ALAAEIEGAG | AAKEQEPQKS | KGKKKKEKKK |
100:
QDFDEDDILK | ELEELSLEAQ | GIKADRETVA | VKPTENNEEE | FTSKDKKKKG |
150:
QKGKKQSFDD | NDSEELEDKD | SKSKKTAKPK | VEMYSGSDDD | DDFNKLPKKA |
200:
KGKAQKSNKK | WDGSEEDEDN | SKKIKERSRI | NSSGESGDES | DEFLQSRKGQ |
250:
KKNQKNKPGP | NIESGNEDDD | ASFKIKTVAQ | KKAEKKERER | KKRDEEKAKL |
300:
RKLKEKEELE | TGKKDQSKQK | ESQRKFEEET | VKSKVTVDTG | VIPASEEKAE |
350:
TPTAAEDDNE | GDKKKKDKKK | KKGEKEEKEK | EKKKGPSKAT | VKAMQEALAK |
400:
LKEEEERQKR | EEEERIKRLE | ELEAKRKEEE | RLEQEKRERK | KQKEKERKER |
450:
LKKEGKLLTK | SQREARARAE | ATLKLLQAQG | VEVPSKDSLP | KKRPIYEDKK |
500:
RKKIPQQLES | KEVSESMELC | AAVEVMEQGV | PEKEETPPPV | EPEEEEDTED |
550:
AGLDDWEAMA | SDEETEKVEG | NKVHIEVKEN | PEEEEEEEEE | EEEDEESEEE |
600:
EEEEGESEGS | EGDEEDEKVS | DEKDSGKTLD | KKPSKEMSSD | SEYDSDDDRT |
650:
KEERAYDKAK | RRIEKRRLEH | SKNVNTEKLR | APIICVLGHV | DTGKTKILDK |
700:
LRHTHVQDGE | AGGITQQIGA | TNVPLEAINE | QTKMIKNFDR | ENVRIPGMLI |
750:
IDTPGHESFS | NLRNRGSSLC | DIAILVVDIM | HGLEPQTIES | INLLKSKKCP |
800:
FIVALNKIDR | LYDWKKSPDS | DVAATLKKQK | KNTKDEFEER | AKAIIVEFAQ |
850:
QGLNAALFYE | NKDPRTFVSL | VPTSAHTGDG | MGSLIYLLVE | LTQTMLSKRL |
900:
AHCEELRAQV | MEVKALPGMG | TTIDVILING | RLKEGDTIIV | PGVEGPIVTQ |
950:
IRGLLLPPPM | KELRVKNQYE | KHKEVEAAQG | VKILGKDLEK | TLAGLPLLVA |
1000:
YKEDEIPVLK | DELIHELKQT | LNAIKLEEKG | VYVQASTLGS | LEALLEFLKT |
1050:
SEVPYAGINI | GPVHKKDVMK | ASVMLEHDPQ | YAVILAFDVR | IERDAQEMAD |
1100:
SLGVRIFSAE | IIYHLFDAFT | KYRQDYKKQK | QEEFKHIAVF | PCKIKILPQY |
1150:
IFNSRDPIVM | GVTVEAGQVK | QGTPMCVPSK | NFVDIGIVTS | IEINHKQVDV |
1200:
AKKGQEVCVK | IEPIPGESPK | MFGRHFEATD | ILVSKISRQS | IDALKDWFRD |
1220:
EMQKSDWQLI | VELKKVFEII |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Human eIF-5B
ELISA Kit for Human eIF-5B
ELISA Kit for Human eIF-5B
CLIA Kit for Human eIF-5B
CLIA Kit for Human eIF-5B
CLIA Kit for Human eIF-5B
Polyclonal Antibody for Human eIF-5B
Polyclonal Antibody for Human eIF-5B
Polyclonal Antibody for Human eIF-5B
Monoclonal Antibody for Human eIF-5B
Monoclonal Antibody for Human eIF-5B
Monoclonal Antibody for Human eIF-5B
R&D Technical Data
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Precision
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Recovery
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Linearity
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT THR-522
tissue :
Cervix carcinoma .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];MUTAGENESIS OF VAL-640; HIS-706 AND ASP-759;CHARACTERIZATION;VARIANT THR-522
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 9-33; 77-94; 106-122; 180-197; 206-224; 285-298; 425-436; 629-644; 653-683; 695-713; 749-757; 766-777; 882-902; 1000-1015; 1044-1055; 1096-1120 AND 1175-1185;PHOSPHORYLATION AT SER-190;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Cervix carcinoma .
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more...
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 89-1220
tissue :
Testis .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 833-1220
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107; SER-113; SER-164 AND SER-214;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-214;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Prostate cancer .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-214;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-214;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
T-cell .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Platelet .
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107; SER-113; TYR-134; SER-135; SER-137; SER-164; SER-182; SER-183; SER-186; SER-190; THR-301; SER-547; SER-560; SER-588 AND SER-595;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107; SER-113 AND SER-164;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; TYR-134; SER-135; SER-137; SER-164; SER-182; SER-183; SER-186; SER-190 AND SER-214;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
17.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
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Vermeulen M.
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Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; SER-135; SER-137; SER-164; SER-182; SER-186; SER-190; SER-214; THR-301; SER-588; SER-589; SER-591 AND SER-595;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107; SER-113; TYR-134; SER-135; SER-137; SER-164; SER-171; SER-214 AND THR-498;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT [LARGE SCALE ANALYSIS] THR-522;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]