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Index > Protein center > IFNG(Gene name) > Human
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  • IFNG (Gene name),
  • Interferon gamma (Protein name ),  IFNG_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    IFNG;
    Protein name:
    Interferon gamma(IFN-gamma);
    Alternative:
    Immune interferon;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    166
    Sequence:
    50:
    MKYTSYILAF | QLCIVLGSLG | CYCQDPYVKE | AENLKKYFNA | GHSDVADNGT | 
    100:
    LFLGILKNWK | EESDRKIMQS | QIVSFYFKLF | KNFKDDQSIQ | KSVETIKEDM | 
    150:
    NVKFFNSNKK | KRDDFEKLTN | YSVTDLNVQR | KAIHELIQVM | AELSPAAKTG | 
    166:
    KRKRSQMLFR | GRRASQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    MIM:
    UniGene:
    String:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human IFN-gamma
    Cat.:
    E0049c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-gamma
    Cat.:
    E0049m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-gamma
    Cat.:
    E0049r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-gamma
    MSDS:
    Please sign in first.
    ELISA Kit for Human IFN-gamma
    Cat.:
    E0049p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-gamma
    Cat.:
    E0049h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-gamma
    Cat.:
    E0049d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human IFN-gamma
    Cat.:
    E0049b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    Cat.:
    U0049b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    Cat.:
    U0049d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    Cat.:
    U0049h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    Cat.:
    U0049c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    Cat.:
    U0049p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    MSDS:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    Cat.:
    U0049r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IFN-gamma
    Cat.:
    U0049m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human IFN-gamma
    Cat.:
    P0049Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IFN-gamma
    Polyclonal Antibody for Human IFN-gamma
    Polyclonal Antibody for Human IFN-gamma
    Polyclonal Antibody for Human IFN-gamma
    Polyclonal Antibody for Human IFN-gamma
    Polyclonal Antibody for Human IFN-gamma
    Cat.:
    P0049Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IFN-gamma
    Cat.:
    P0049Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human IFN-gamma
    Monoclonal Antibody for Human IFN-gamma
    Monoclonal Antibody for Human IFN-gamma
    Cat.:
    M0049h
    Price:
    Please sign in first.
    Packing:
    40ug
    Monoclonal Antibody for Human IFN-gamma
    Monoclonal Antibody for Human IFN-gamma
    Monoclonal Antibody for Human IFN-gamma
    Monoclonal Antibody for Human IFN-gamma
    Monoclonal Antibody for Human IFN-gamma
    Protein for Human IFN-gamma
    Protein for Human IFN-gamma
    Protein for Human IFN-gamma
    Protein for Human IFN-gamma
    Cat.:
    R0049h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human IFN-gamma
    Cat.:
    R0049m
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human IFN-gamma
    Protein for Human IFN-gamma
    Protein for Human IFN-gamma

    R&D Technical Data
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    s

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.6%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.9%

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    Recovery
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    Recovery was determined by spiking various levels of IFNG into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    98

    96-100

    Plasma

    99

    97-101

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of IFNG and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    95-104%

    96-100%

    92-98%

    102-105%

    EDTA plasma(n=5)

    89-95%

    93-105%

    98-104%

    93-97%

    heparin plasma(n=5)

    96-103%

     

    97-101%

    99-105%

    91-98%

     

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    References
    1. 1.
      "Structure of the human immune interferon gene."
      Gray P.W. , Goeddel D.V.
      Nature298:859-863(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning and expression of a novel variant of human interferon-gamma cDNA."
      Nishi T. , Fujita T. , Nishi-Takaoka C. , Saito A. , Matsumoto T. , Sato M. , Oka T. , Itoh S. , Yip Y.K. , Vilcek J. , Taniguchi T.
      J. Biochem.97:153-159(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Cloning and structure of the human immune interferon-gamma chromosomal gene."
      Taya Y. , Devos R. , Tavernier J. , Cheroutre H. , Engler G. , Fiers W.
      EMBO J.1:953-958(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells."
      Devos R. , Cheroutre H. , Taya Y. , Degrave W. , van Heuverswyn H. , Fiers W.
      Nucleic Acids Res.10:2487-2501(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      Chikara S.K. , Jaiswal P. , Sharma G.
      Submitted (2003-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLN-160
    7. 7.
      SeattleSNPs variation discovery resource
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    8. 8.
      "Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
      Goshima N. , Kawamura Y. , Fukumoto A. , Miura A. , Honma R. , Satoh R. , Wakamatsu A. , Yamamoto J. , Kimura K. , Nishikawa T. , Andoh T. , Iida Y. , Ishikawa K. , Ito E. , Kagawa N. , Kaminaga C. , Kanehori K. , Kawakami B. , more...
      Nat. Methods5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Blood.
    11. 11.
      "Natural human interferon-gamma. Complete amino acid sequence and determination of sites of glycosylation."
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