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Index > Protein center > IGF1(Gene name) > Human
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  • IGF1 (Gene name),
  • Insulin-like growth factor I (Protein name ),  IGF1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    IGF1(IBP1);
    Protein name:
    Insulin-like growth factor I(IGF-I);
    Alternative:
    Somatomedin-C;Mechano growth factor(MGF);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    195
    Sequence:
    50:
    MGKISSLPTQ | LFKCCFCDFL | KVKMHTMSSS | HLFYLALCLL | TFTSSATAGP | 
    100:
    ETLCGAELVD | ALQFVCGDRG | FYFNKPTGYG | SSSRRAPQTG | IVDECCFRSC | 
    150:
    DLRRLEMYCA | PLKPAKSARS | VRAQRHTDMP | KTQKYQPPST | NKNTKSQRRK | 
    195:
    GWPKTHPGGE | QKEGTEASLQ | IRGKKKEQRR | EIGSRNAECR | GKKGK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    Pfam:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human IGF-I
    Cat.:
    E0050r
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human IGF-I
    MSDS:
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    ELISA Kit for Human IGF-I
    Cat.:
    E0050p
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IGF-I
    Cat.:
    E0050m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IGF-I
    Cat.:
    E0050h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IGF-I
    Cat.:
    E0050d
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IGF-I
    Cat.:
    E0050c
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IGF-I
    Cat.:
    E0050b
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human IGF-I
    Cat.:
    U0050b
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human IGF-I
    Cat.:
    U0050c
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human IGF-I
    Cat.:
    U0050d
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IGF-I
    Cat.:
    U0050h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IGF-I
    Cat.:
    U0050m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IGF-I
    Cat.:
    U0050p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IGF-I
    MSDS:
    Please sign in first.
    CLIA Kit for Human IGF-I
    Cat.:
    U0050r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Human IGF-I
    Cat.:
    P0050Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IGF-I
    Cat.:
    P0050Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IGF-I
    Polyclonal Antibody for Human IGF-I
    Cat.:
    P0050Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IGF-I
    Polyclonal Antibody for Human IGF-I
    Polyclonal Antibody for Human IGF-I
    Polyclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Monoclonal Antibody for Human IGF-I
    Protein for Human IGF-I
    Protein for Human IGF-I
    Protein for Human IGF-I
    Protein for Human IGF-I
    Protein for Human IGF-I
    Protein for Human IGF-I
    Cat.:
    R0050h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human IGF-I
    Cat.:
    R0050m
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human IGF-I

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      "Organization of the human genes for insulin-like growth factors I and II."
      de Pagter-Holthuizen P. , van Schaik F.M.A. , Verduijn G.M. , van Ommen G.J.B. , Bouma B.N. , Jansen M. , Sussenbach J.S.
      FEBS Lett.195:179-184(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Complete characterization of the human IGF-I nucleotide sequence isolated from a newly constructed adult liver cDNA library."
      le Bouc Y. , Dreyer D. , Jaeger F. , Binoux M. , Sondermeyer P.
      FEBS Lett.196:108-112(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    4. 4.
      "Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides."
      Rotwein P. , Pollock K.M. , Didier D.K. , Krivi G.G.
      J. Biol. Chem.261:4828-4832(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Two insulin-like growth factor I messenger RNAs are expressed in human liver."
      Rotwein P.
      Proc. Natl. Acad. Sci. U.S.A.83:77-81(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    6. 6.
      "A novel human insulin-like growth factor I messenger RNA is expressed in normal and tumor cells."
      Tobin G. , Yee D. , Brunner N. , Rotwein P.
      Mol. Endocrinol.4:1914-1920(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
    7. 7.
      "Complete nucleotide sequence of the high molecular weight human IGF-I mRNA."
      Steenbergh P.H. , Koonen-Reemst A.M.C.B. , Cleutjens C.B.J.M. , Sussenbach J.S.
      Biochem. Biophys. Res. Commun.175:507-514(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Liver.
    8. 8.
      "Characterization of two cDNAs encoding insulin-like growth factor 1 (IGF-1) in the human fetal brain."
      Sandberg-Nordqvist A.-C. , Staehlbom P.-A. , Lake M. , Sara V.R.
      Brain Res. Mol. Brain Res.12:275-277(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Brain.
    9. 9.
      "Characterization of insulin-like growth factor 1 in human primary brain tumors."
      Sandberg-Nordqvist A.-C. , Staehlbom P.-A. , Reinecke M. , Collins V.P. , von Holst H. , Sara V.
      Cancer Res.53:2475-2478(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Brain.
    10. 10.
      NIEHS SNPs program
      Submitted (2003-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    11. 11.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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      Zoidis E. , Ghirlanda-Keller C. , Schmid C.
      Mol. Cell. Biochem.348:33-42(2011) [PubMed] [Europe PMC] [Abstract]
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      "SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients."
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      Nature503:267-271(2013) [PubMed] [Europe PMC] [Abstract]
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN IGF1 DEFICIENCY
    23. 23.
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