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Index > Protein center > IGHG3(Gene name) > Human
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  • IGHG3 (Gene name),
  • Ig gamma-3 chain C region (Protein name ),  IGHG3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IGHG3;
    Protein name:
    Ig gamma-3 chain C region;
    Alternative:
    Heavy chain disease protein;HDC;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimer linked by 12 disulfide bonds; it has an extra interchain disulfide bond at position 7 in addition to the 11 normally present in the hinge region.
    Function:
    N/A
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    377
    Sequence:
    50:
    ASTKGPSVFP | LAPCSRSTSG | GTAALGCLVK | DYFPEPVTVS | WNSGALTSGV | 
    100:
    HTFPAVLQSS | GLYSLSSVVT | VPSSSLGTQT | YTCNVNHKPS | NTKVDKRVEL | 
    150:
    KTPLGDTTHT | CPRCPEPKSC | DTPPPCPRCP | EPKSCDTPPP | CPRCPEPKSC | 
    200:
    DTPPPCPRCP | APELLGGPSV | FLFPPKPKDT | LMISRTPEVT | CVVVDVSHED | 
    250:
    PEVQFKWYVD | GVEVHNAKTK | PREEQYNSTF | RVVSVLTVLH | QDWLNGKEYK | 
    300:
    CKVSNKALPA | PIEKTISKTK | GQPREPQVYT | LPPSREEMTK | NQVSLTCLVK | 
    350:
    GFYPSDIAVE | WESSGQPENN | YNTTPPMLDS | DGSFFLYSKL | TVDKSRWQQG | 
    377:
    NIFSCSVMHE | ALHNRFTQKS | LSLSPGK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ig gamma-3 chain C region
    CLIA Kit for Human Ig gamma-3 chain C region
    Polyclonal Antibody for Human Ig gamma-3 chain C region
    Monoclonal Antibody for Human Ig gamma-3 chain C region
    Protein for Human Ig gamma-3 chain C region

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes."
      Huck S. , Fort P. , Crawford D.H. , Lefranc M.-P. , Lefranc G.
      Nucleic Acids Res.14:1779-1789(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "Primary structure of human gamma 3 immunoglobulin deletion mutant: gamma 3 heavy-chain disease protein Wis."
      Frangione B. , Rosenwasser E. , Prelli F. , Franklin E.C.
      Biochemistry19:4304-4308(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE (VARIANT WIS);SUBUNIT
    4. 4.
      "Primary structure of the 'hinge' region of human IgG3. Probable quadruplication of a 15-amino acid residue basic unit."
      Michaelsen T.E. , Frangione B. , Franklin E.C.
      J. Biol. Chem.252:883-889(1977) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 146-376 (VARIANT WIS/VARIANT ZUC)
    5. 5.
      "The amino acid sequence of 'heavy chain disease' protein ZUC. Structure of the Fc fragment of immunoglobulin G3."
      Wolfenstein-Todel C. , Frangione B. , Prelli F. , Franklin E.C.
      Biochem. Biophys. Res. Commun.71:907-914(1976) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 59-289 (VARIANT WIS/VARIANT ZUC)
    6. 6.
      "Gamma heavy chain disease in man: cDNA sequence supports partial gene deletion model."
      Alexander A. , Steinmetz M. , Barritault D. , Frangione B. , Franklin E.C. , Hood L. , Buxbaum J.N.
      Proc. Natl. Acad. Sci. U.S.A.79:3260-3264(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 99-377 (VARIANT OMM)
    7. 7.
      "Structure of human immunoglobulin gamma genes: implications for evolution of a gene family."
      Takahashi N. , Ueda S. , Obata M. , Nikaido T. , Nakai S. , Honjo T.
      Cell29:671-679(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 48-59
    8. 8.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-227 AND ASN-322
      tissue: Plasma.
    9. 9.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-227
      tissue: Liver.
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