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Index > Protein center > Cd101(Gene name) > Mouse
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  • Cd101 (Gene name),
  • Immunoglobulin superfamily member 2 (Protein name ),  IGSF2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cd101(Igsf2);
    Protein name:
    Immunoglobulin superfamily member 2(IgSF2);
    Alternative:
    Glu-Trp-Ile EWI motif-containing protein 101(EWI-101);
    CD:
    CD101;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1033
    Sequence:
    50:
    MACILCVASL | FLSLTKFSIG | QREVKIQEGP | LYRAEGYPVS | IRCTVSGHQG | 
    100:
    PSTQDFRWSI | YLPSAPTKEV | QIISTKDAGF | SYAVYAQRVQ | SKEIYIERLQ | 
    150:
    GDSVLLHISK | LQMKDAGEYE | CHTPNTDGKY | FGSYSAKTNL | TVVPDTLSAT | 
    200:
    MPSQTLSKKE | GEPLELTCET | TKATVQHTHL | SLTWYLMQEG | GGSQATEIVS | 
    250:
    LSKDFVLTPG | SSYADRFVAG | DVRLDKLGAT | SFRLSVGKLQ | PSDQGQVFCE | 
    300:
    ATEWIQDPDE | TWTLITRKQT | DQTALRIQPA | ARDFTVSITA | SSSPDEGKPL | 
    350:
    ELVCLAVGRD | GNPQLQGVWF | LNGKEIAQTD | AGGVLDLKRD | YRDRASQGQL | 
    400:
    QVSKLSAQTF | SLKIFSVGPE | DVGTYSCEVA | EVARTQMGSW | QVLQRKQSPG | 
    450:
    YRVQLREPAA | RSVTVSAEQR | TVWEGETLTL | LCKAAGDVSA | LSVSWWLTPQ | 
    500:
    DQSTPVFVAG | MGQDGTVQLG | VSSPGPAHRG | NRRLEKVDWA | TFRLEIASAM | 
    550:
    VTDSGTYECR | VSERLQNQAK | GLQSTQKISV | TVKSLKSSLR | VNLMSRQPQV | 
    600:
    MLAHTFHLSC | VVRANYSDLK | LPFSVTWQFQ | PAGSGAFHRL | IRIAHNGTVE | 
    650:
    WGDVLSQIHR | KTKVSQSFFR | SQLQIYDAAM | EETGVYRCTV | EVYDRDSICT | 
    700:
    SGPARVSATS | NLLMITVTFP | ESKLSVNSSS | QVQELSISSS | TQIECAILSR | 
    750:
    SAGNLPLSII | WYFSSVSANA | SYLKILEMDQ | SSVVKYGDEF | QTPRSKQKFY | 
    800:
    SEKVSQDLFL | LNILSVEDSD | QGHYHCAVEE | WLLSTNDTWQ | KLERKTSGLT | 
    850:
    ELKLRPTGSQ | VHVSKVNWTG | NATEYGEAGF | SCSLDGSGST | ASLYSVTWYR | 
    900:
    GRGTATATAA | AVANATATIT | APAGSQMLVH | LQYDGLLQYG | REGSRRLQHC | 
    950:
    YRSSPTDFVL | KLHRVEMEDA | GIYWCRVTEW | QQHGHPGKWI | NQASGESQRM | 
    1000:
    VLRVLRSEPT | VSSLICSSGP | LLHFLIVCPF | VMLLLLATSF | LCLYRKARKL | 
    1033:
    SQLSLSAKKE | KALWVGMRKT | SLQKEAGEES | GHY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse IgSF2
    ELISA Kit for Mouse IgSF2
    CLIA Kit for Mouse IgSF2
    CLIA Kit for Mouse IgSF2
    Polyclonal Antibody for Mouse IgSF2
    Polyclonal Antibody for Mouse IgSF2
    Monoclonal Antibody for Mouse IgSF2
    Monoclonal Antibody for Mouse IgSF2
    Protein for Mouse IgSF2
    Protein for Mouse IgSF2

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice."
      Penha-Goncalves C. , Moule C. , Smink L.J. , Howson J. , Gregory S. , Rogers J. , Lyons P.A. , Suttie J.J. , Lord C.J. , Peterson L.B. , Todd J.A. , Wicker L.S.
      Diabetes52:1551-1556(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: NOD.B6.
      strain: NOD/MrkTac.
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