IL21 ELISA Kit for Human(Homo sapiens) | EIAab.comIL21 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > IL21(Gene name) > Human

IL21 (Gene name),

Interleukin-21 (Protein name ), IL21_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

IL21;

Protein name:

Interleukin-21(IL-21);

Alternative:

Za11;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Function:

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

155

Sequence:

50:

100:

150:

155:

GSEDS

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Hs.567559

MIM:

605384

SMR:

Q9HBE4

STRING:

9606.ENSP00000264497

KEGG:

hsa:59067

String:

Q9HBE4

Pfam:

PF02372

Uniprot:

Q9HBE4

FOR

ELISA Kit for Human IL-21

Cat.:

E1688b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human IL-21

Cat.:

E1688d

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human IL-21

Cat.:

E1688p

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human IL-21

Cat.:

E1688h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human IL-21

Cat.:

E1688m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human IL-21

Cat.:

E1688r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human IL-21

Cat.:

U1688r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human IL-21

Cat.:

U1688p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human IL-21

Cat.:

U1688m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human IL-21

Cat.:

U1688h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human IL-21

Cat.:

U1688b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human IL-21

Cat.:

U1688d

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human IL-21

Cat.:

P1688Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human IL-21

Cat.:

P1688Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human IL-21

Cat.:

P1688Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human IL-21

Monoclonal Antibody for Human IL-21

Protein for Human IL-21

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function."
Parrish-Novak J. , Dillon S.R. , Nelson A. , Hammond A. , Sprecher C. , Gross J.A. , Johnston J. , Madden K. , Xu W. , West J. , Schrader S. , Burkhead S. , Heipel M. , Brandt C. , Kuijper J.L. , Kramer J. , Conklin D. , Presnell S.R. , more...
Nature408:57-63(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
2.

"Cloning and characterization of an isoform of interleukin-21."
Rahman M. , Nara H. , Onoda T. , Araki A. , Li J. , Hoshino T. , Asao H.
FEBS Lett.581:4001-4009(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
3.

SeattleSNPs variation discovery resource
Submitted (2004-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
6.

"IFN-alpha regulates IL-21 and IL-21R expression in human NK and T cells."
Strengell M. , Julkunen I. , Matikainen S.
J. Leukoc. Biol.76:416-422(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses."
Sivakumar P.V. , Foster D.C. , Clegg C.H.
Immunology112:177-182(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
8.

"The existence of multiple conformers of interleukin-21 directs engineering of a superpotent analogue."
Bondensgaard K. , Breinholt J. , Madsen D. , Omkvist D.H. , Kang L. , Worsaae A. , Becker P. , Schioedt C.B. , Hjorth S.A.
J. Biol. Chem.282:23326-23336(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 23-155;DISULFIDE BONDS
9.

"Crystal structure of interleukin-21 receptor (IL-21R) bound to IL-21 reveals that sugar chain interacting with WSXWS motif is integral part of IL-21R."
Hamming O.J. , Kang L. , Svensson A. , Karlsen J.L. , Rahbek-Nielsen H. , Paludan S.R. , Hjorth S.A. , Bondensgaard K. , Hartmann R.
J. Biol. Chem.287:9454-9460(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 23-155 IN COMPLEX WITH IL21R;DISULFIDE BONDS
10.

"Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency."
Salzer E. , Kansu A. , Sic H. , Majek P. , Ikinciogullari A. , Dogu F.E. , Prengemann N.K. , Santos-Valente E. , Pickl W.F. , Bilic I. , Ban S.A. , Kuloglu Z. , Demir A.M. , Ensari A. , Colinge J. , Rizzi M. , Eibel H. , Boztug K.
J. Allergy Clin. Immunol.133:1651-1660(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CVID11 PRO-49;CHARACTERIZATION OF VARIANT CVID11 PRO-49

Product Feedback Wall

* Email:
*Comments: