Il21 ELISA Kit for Mouse(Mus musculus) | EIAab.comIl21 ELISA Kit for Mouse(Mus musculus)

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Il21 (Gene name),

Interleukin-21 (Protein name ), IL21_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Il21;

Protein name:

Interleukin-21(IL-21);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

146

Sequence:

50:

100:

146:

PARRGGKKQK | HIAKCPSCDS | YEKRTPKEFL | ERLKWLLQKM | IHQHLS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9ES17

String:

Q9ES17

KEGG:

mmu:60505

UniGene:

Mm.157689

Pfam:

PF02372

STRING:

10090.ENSMUSP00000029273

Uniprot:

Q9ES17

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ELISA Kit for Mouse IL-21

Cat.:

E1688b

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Packing:

96T

ELISA Kit for Mouse IL-21

Cat.:

E1688d

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ELISA Kit for Mouse IL-21

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E1688p

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ELISA Kit for Mouse IL-21

Cat.:

E1688h

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ELISA Kit for Mouse IL-21

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E1688m

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ELISA Kit for Mouse IL-21

Cat.:

E1688r

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CLIA Kit for Mouse IL-21

Cat.:

U1688r

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96T

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CLIA Kit for Mouse IL-21

Cat.:

U1688p

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96T

CLIA Kit for Mouse IL-21

Cat.:

U1688m

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Looking for manual.

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96T

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CLIA Kit for Mouse IL-21

Cat.:

U1688h

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Looking for manual.

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96T

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CLIA Kit for Mouse IL-21

Cat.:

U1688b

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96T

CLIA Kit for Mouse IL-21

Cat.:

U1688d

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96T

Polyclonal Antibody for Mouse IL-21

Cat.:

P1688Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse IL-21

Cat.:

P1688Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse IL-21

Cat.:

P1688Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse IL-21

Monoclonal Antibody for Mouse IL-21

Protein for Mouse IL-21

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function."
Parrish-Novak J. , Dillon S.R. , Nelson A. , Hammond A. , Sprecher C. , Gross J.A. , Johnston J. , Madden K. , Xu W. , West J. , Schrader S. , Burkhead S. , Heipel M. , Brandt C. , Kuijper J.L. , Kramer J. , Conklin D. , Presnell S.R. , more...
Nature408:57-63(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
2.

"Mouse interleukin 21 can improve the anti-tumor effect of LAK cells."
Guobing C. , Jun D. , Junsong C. , Fenshu Z.
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
3.

"IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity."
Kasaian M.T. , Whitters M.J. , Carter L.L. , Lowe L.D. , Jussif J.M. , Deng B. , Johnson K.A. , Witek J.S. , Senices M. , Konz R.F. , Wurster A.L. , Donaldson D.D. , Collins M. , Young D.A. , Grusby M.J.
Immunity16:559-569(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
4.

"Interleukin-21 inhibits dendritic cell activation and maturation."
Brandt K. , Bulfone-Paus S. , Foster D.C. , Rueckert R.
Blood102:4090-4098(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
5.

"IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells."
Pene J. , Gauchat J.-F. , Lecart S. , Drouet E. , Guglielmi P. , Boulay V. , Delwail A. , Foster D. , Lecron J.C. , Yssel H.
J. Immunol.172:5154-5157(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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