IL4R ELISA Kit for Pig(Sus scrofa) | EIAab.comIL4R ELISA Kit for Pig(Sus scrofa)

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IL4R (Gene name),

Interleukin-4 receptor subunit alpha (Protein name ), IL4RA_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

IL4R;

Protein name:

Interleukin-4 receptor subunit alpha(IL-4 receptor subunit alpha;IL-4R subunit alpha;IL-4R-alpha;IL-4RA);

Alternative:

CD:

CD124;

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

The functional IL4 receptor is formed by initial binding of IL4 to IL4R. Subsequent recruitment to the complex of the common gamma chain, in immune cells, creates a type I receptor and, in non-immune cells, of IL13RA1 forms a type II receptor. IL4R can also interact with the IL13/IL13RA1 complex to form a similar type II receptor. Interacts with PIK3C3 (By similarity). Interacts with the SH2-containing phosphatases, PTPN6/SHIP1, PTPN11/SHIP2 and INPP5D/SHIP (By similarity). Interacts with JAK1 through a Box 1-containing region (By similarity). In Th1 cells, binds the N-terminal 50AA of SOCS5, which inhibits JAK1 interaction, STAT6 activation and Th2 cell differentiation. SOCS5 interaction is independent of tyrosine phosphorylation.

Function:

Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammmation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

830

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

830:

QITPSNVQSS | SQTPTAVAML | SPGPACMDTS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

ssc:397614

Pfam:

PF09238

UniGene:

Ssc.17244

SMR:

Q863Z5

Uniprot:

Q863Z5

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ELISA Kit for Pig IL-4 receptor subunit alpha

Cat.:

E2031h

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96T

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ELISA Kit for Pig IL-4 receptor subunit alpha

Cat.:

E2031m

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96T

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ELISA Kit for Pig IL-4 receptor subunit alpha

Cat.:

E2031r

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96T

ELISA Kit for Pig IL-4 receptor subunit alpha

Cat.:

E2031p

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Packing:

96T

CLIA Kit for Pig IL-4 receptor subunit alpha

Cat.:

U2031r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Pig IL-4 receptor subunit alpha

Cat.:

U2031m

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MSDS:

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Packing:

96T

CLIA Kit for Pig IL-4 receptor subunit alpha

Cat.:

U2031p

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MSDS:

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Packing:

96T

CLIA Kit for Pig IL-4 receptor subunit alpha

Cat.:

U2031h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Pig IL-4 receptor subunit alpha

Cat.:

P2031Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig IL-4 receptor subunit alpha

Cat.:

P2031Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Pig IL-4 receptor subunit alpha

Cat.:

P2031Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Pig IL-4 receptor subunit alpha

Protein for Pig IL-4 receptor subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of the swine IL-4 receptor alpha and IL-13 receptor alpha 1 chains: effects of experimental Toxoplasma gondii and Ascaris suum infections on tissue mRNA levels."
Zarlenga D.S. Jr. , Dawson H. , Solano-Aguilar G. , Urban J.F. Jr.
Submitted (2003-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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