Il4r ELISA Kit for Rat(Rattus norvegicus) | EIAab.comIl4r ELISA Kit for Rat(Rattus norvegicus)

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Il4r (Gene name),

Interleukin-4 receptor subunit alpha (Protein name ), IL4RA_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Il4r(Il4ra);

Protein name:

Interleukin-4 receptor subunit alpha(IL-4 receptor subunit alpha;IL-4R subunit alpha;IL-4R-alpha;IL-4RA);

Alternative:

CD:

CD124;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

The functional IL4 receptor is formed by initial binding of IL4 to IL4R. Subsequent recruitment to the complex of the common gamma chain, in immune cells, creates a type I receptor and, in non-immune cells, of IL13RA1 forms a type II receptor. IL4R can also interact with the IL13/IL13RA1 complex to form a similar type II receptor. Interacts with PIK3C3 (By similarity). Interacts with the SH2-containing phosphatases, PTPN6/SHIP1, PTPN11/SHIP2 and INPP5D/SHIP (By similarity). Interacts with JAK1 through a Box 1-containing region (By similarity). In Th1 cells, binds the N-terminal 50 amino acids of SOCS5, which inhibits JAK1 interaction, STAT6 activation and Th2 cell differentiation. SOCS5 interaction is independent of tyrosine phosphorylation.

Function:

Isoform 2 (soluble form) inhibits IL4-induced spleen cell proliferation.

Subcellular Location:

Isoform 2 Secreted

Protein Attributes:

Sequence length:

801

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

801:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF09238

UniGene:

Rn.10471

KEGG:

rno:25084

String:

Q63257

Uniprot:

Q63257

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ELISA Kit for Rat IL-4 receptor subunit alpha

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E2031h

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96T

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ELISA Kit for Rat IL-4 receptor subunit alpha

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E2031m

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96T

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ELISA Kit for Rat IL-4 receptor subunit alpha

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E2031r

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96T

ELISA Kit for Rat IL-4 receptor subunit alpha

Cat.:

E2031p

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96T

CLIA Kit for Rat IL-4 receptor subunit alpha

Cat.:

U2031r

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MSDS:

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Packing:

96T

CLIA Kit for Rat IL-4 receptor subunit alpha

Cat.:

U2031m

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MSDS:

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Packing:

96T

CLIA Kit for Rat IL-4 receptor subunit alpha

Cat.:

U2031p

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat IL-4 receptor subunit alpha

Cat.:

U2031h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Rat IL-4 receptor subunit alpha

Cat.:

P2031Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat IL-4 receptor subunit alpha

Cat.:

P2031Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat IL-4 receptor subunit alpha

Cat.:

P2031Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat IL-4 receptor subunit alpha

Protein for Rat IL-4 receptor subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The rat interleukin 4 receptor: coevolution of ligand and receptor."
Richter G. , Hein G. , Blankenstein T. , Diamantstein T.
Cytokine7:237-241(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: Wistar.
tissue: Spleen.
2.

"Identification of soluble interleukin-4 receptor in rat glomerular epithelial cells."
Chen G. , Nagasawa R. , Imasawa T. , Eto Y. , Kikuchi K. , Maruyama N.
Biochim. Biophys. Acta1452:79-88(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
tissue: Kidney.

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