IL7R ELISA Kit for Human(Homo sapiens) | EIAab.comIL7R ELISA Kit for Human(Homo sapiens)

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Index > Protein center > IL7R(Gene name) > Human

IL7R (Gene name),

Interleukin-7 receptor subunit alpha (Protein name ), IL7RA_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

IL7R;

Protein name:

Interleukin-7 receptor subunit alpha(IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA);

Alternative:

CDw127;

CD:

CD127;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

The IL7 receptor is an heterodimer of IL7R and IL2RG. The TSLP receptor is an heterodimer of CRLF2 and IL7R.

Function:

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Subcellular Location:

Isoform 4 Secreted

Protein Attributes:

Sequence length:

459

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

459:

TMSSFYQNQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.591742

SMR:

P16871

KEGG:

hsa:3575

MIM:

146661

String:

P16871

Pfam:

PF00041

Uniprot:

P16871

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ELISA Kit for Human IL-7 receptor subunit alpha

Cat.:

E2101h

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Manual:

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Packing:

96T

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ELISA Kit for Human IL-7 receptor subunit alpha

Cat.:

E2101m

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MSDS:

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Packing:

96T

CLIA Kit for Human IL-7 receptor subunit alpha

Cat.:

U2101h

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Manual:

Looking for manual.

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96T

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CLIA Kit for Human IL-7 receptor subunit alpha

Cat.:

U2101m

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Packing:

96T

Polyclonal Antibody for Human IL-7 receptor subunit alpha

Cat.:

P2101Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human IL-7 receptor subunit alpha

Cat.:

P2101Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human IL-7 receptor subunit alpha

Protein for Human IL-7 receptor subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily."
Goodwin R.G. , Friend D. , Ziegler S.F. , Jerzy R. , Falk B.A. , Gimpel S. , Cosman D. , Dower S.K. , March C.J. , Namen A.E. , Park L.S.
Cell60:941-951(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ALTERNATIVE SPLICING;VARIANT VAL-356
tissue: B-cell.
2.

"Organization of the murine and human interleukin-7 receptor genes: two mRNAs generated by differential splicing and presence of a type I-interferon-inducible promoter."
Pleiman C.M. , Gimpel S.D. , Park L.S. , Harada H. , Taniguchi T. , Ziegler S.F.
Mol. Cell. Biol.11:3052-3059(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);VARIANT VAL-356
3.

"Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency."
Puel A. , Ziegler S.F. , Buckley R.H. , Leonard W.J.
Nat. Genet.20:394-397(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANTS T(-)/B(+)/NK(+) SCID ILE-66 AND VAL-138;VARIANT ILE-244
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4);VARIANT VAL-356
tissue: Spleen.
5.

SeattleSNPs variation discovery resource
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANTS T(-)/B(+)/NK(+) SCID ILE-66 AND VAL-138;VARIANTS ASP-113 AND ILE-244
6.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANTS T(-)/B(+)/NK(+) SCID ILE-66 AND VAL-138
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS T(-)/B(+)/NK(+) SCID ILE-66 AND VAL-138;VARIANT VAL-356
tissue: Testis.
8.

"Structural and biophysical studies of the human IL-7/IL-7Ralpha complex."
McElroy C.A. , Dohm J.A. , Walsh S.T.
Structure17:54-65(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 21-239 IN COMPLEX WITH IL7;SUBUNIT;GLYCOSYLATION AT ASN-49; ASN-65 AND ASN-151;DISULFIDE BONDS
9.

"A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency."
Roifman C.M. , Zhang J. , Chitayat D. , Sharfe N.
Blood96:2803-2807(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT T(-)/B(+)/NK(+) SCID SER-132
10.

"Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis."
Gregory S.G. , Schmidt S. , Seth P. , Oksenberg J.R. , Hart J. , Prokop A. , Caillier S.J. , Ban M. , Goris A. , Barcellos L.F. , Lincoln R. , McCauley J.L. , Sawcer S.J. , Compston D.A. , Dubois B. , Hauser S.L. , Garcia-Blanco M.A. , Pericak-Vance M.A. , more...
Nat. Genet.39:1083-1091(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ILE-244;ASSOCIATION WITH MS3

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