Protein name:
Importin subunit alpha-8 ;
Alternative:
Karyopherin subunit alpha-7 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds very efficiently to importin subunit beta-1/KPNB1 via the IBB domain; this complex dissociates in the presence of RAN-GTP. Shows a limited binding to the RB1 nuclear localization signal (NLS), but not to the SV40, nor NPM1 NLSs.
Function:
Functions in nuclear protein import.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MPTLDAPEER | RRKFKYRGKD | VSLRRQQRMA | VSLELRKAKK | DEQTLKRRNI |
100:
TSFCPDTPSE | KTAKGVAVSL | TLGEIIKGVN | SSDPVLCFQA | TQTARKMLSQ |
150:
EKNPPLKLVI | EAGLIPRMVE | FLKSSLYPCL | QFEAAWALTN | IASGTSEQTR |
200:
AVVEGGAIQP | LIELLSSSNV | AVCEQAVWAL | GNIAGDGPEF | RDNVITSNAI |
250:
PHLLALISPT | LPITFLRNIT | WTLSNLCRNK | NPYPCDTAVK | QILPALLHLL |
300:
QHQDSEVLSD | ACWALSYLTD | GSNKRIGQVV | NTGVLPRLVV | LMTSSELNVL |
350:
TPSLRTVGNI | VTGTDEQTQM | AIDAGMLNVL | PQLLQHNKPS | IQKEAAWALS |
400:
NVAAGPCHHI | QQLLAYDVLP | PLVALLKNGE | FKVQKEAVWM | VANFATGATM |
450:
DQLIQLVHSG | VLEPLVNLLT | APDVKIVLII | LDVISCILQA | AEKRSEKENL |
500:
CLLIEELGGI | DRIEALQLHE | NRQIGQSALN | IIEKHFGEEE | DESQTLLSQV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Pig
Mouse
ELISA Kit for Human Importin subunit alpha-8
ELISA Kit for Human Importin subunit alpha-8
ELISA Kit for Human Importin subunit alpha-8
ELISA Kit for Human Importin subunit alpha-8
CLIA Kit for Human Importin subunit alpha-8
CLIA Kit for Human Importin subunit alpha-8
CLIA Kit for Human Importin subunit alpha-8
CLIA Kit for Human Importin subunit alpha-8
Polyclonal Antibody for Human Importin subunit alpha-8
Polyclonal Antibody for Human Importin subunit alpha-8
Polyclonal Antibody for Human Importin subunit alpha-8
Polyclonal Antibody for Human Importin subunit alpha-8
Monoclonal Antibody for Human Importin subunit alpha-8
Monoclonal Antibody for Human Importin subunit alpha-8
Monoclonal Antibody for Human Importin subunit alpha-8
Monoclonal Antibody for Human Importin subunit alpha-8
Protein for Human Importin subunit alpha-8
Protein for Human Importin subunit alpha-8
Protein for Human Importin subunit alpha-8
Protein for Human Importin subunit alpha-8
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;INTERACTION WITH KPNB1 AND RB1
tissue :
Prostatic adenocarcinoma .
2.
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Science300:767-772(2003)
[
PubMed ]
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]