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Index > Protein center > IMPA1(Gene name) > Bovine
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  • IMPA1 (Gene name),
  • Inositol monophosphatase 1 (Protein name ),  IMPA1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    IMPA1(IMPA);
    Protein name:
    Inositol monophosphatase 1(IMP 1;IMPase 1);
    Alternative:
    Lithium-sensitive myo-inositol monophosphatase A1;Inositol-1(or 4)-monophosphatase 1;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    277
    Sequence:
    50:
    MADPWQECMD | YAVTLAGQAG | EVVREALKNE | MNIMVKSSPA | DLVTATDQKV | 
    100:
    EKMLITSIKE | KYPSHSFIGE | ESVAAGEKSI | LTDNPTWIID | PIDGTTNFVH | 
    150:
    GFPFVAVSIG | FVVNKKMEFG | IVYSCLEDKM | YTGRKGKGAF | CNGQKLQVSH | 
    200:
    QEDITKSLLV | TELGSSRTPE | TVRIILSNIE | RLLCLPIHGI | RGVGTAALNM | 
    250:
    CLVAAGAADA | YYEMGIHCWD | VAGAGIIVTE | AGGVLLDVTG | GPFDLMSRRV | 
    277:
    IASSNKTLAE | RIAKEIQIIP | LQRDDED
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine IMP 1
    Cat.:
    E1404h
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    96T
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    ELISA Kit for Bovine IMP 1
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    E1404b
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    ELISA Kit for Bovine IMP 1
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    E1404p
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    96T
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    ELISA Kit for Bovine IMP 1
    Cat.:
    E1404r
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    96T
    ELISA Kit for Bovine IMP 1
    Cat.:
    E1404m
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    Packing:
    96T
    CLIA Kit for Bovine IMP 1
    Cat.:
    U1404r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine IMP 1
    Cat.:
    U1404b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine IMP 1
    Cat.:
    U1404p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine IMP 1
    Cat.:
    U1404h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine IMP 1
    Cat.:
    U1404m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Bovine IMP 1
    Cat.:
    P1404Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine IMP 1
    Cat.:
    P1404Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine IMP 1
    Cat.:
    P1404Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine IMP 1
    Polyclonal Antibody for Bovine IMP 1
    Monoclonal Antibody for Bovine IMP 1
    Monoclonal Antibody for Bovine IMP 1
    Monoclonal Antibody for Bovine IMP 1
    Monoclonal Antibody for Bovine IMP 1
    Monoclonal Antibody for Bovine IMP 1
    Protein for Bovine IMP 1
    Protein for Bovine IMP 1
    Protein for Bovine IMP 1
    Protein for Bovine IMP 1
    Protein for Bovine IMP 1

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    References
    1. 1.
      "Cloning and expression of bovine brain inositol monophosphatase."
      Diehl R.E. , Whiting P. , Potter J. , Gee N. , Ragan C.I. , Linemeyer D. , Schoepfer R. , Bennett C. , Dixon R.A.F.
      J. Biol. Chem.265:5946-5949(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      tissue: Brain.
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Fetal pons.
    3. 3.
      "Brain inositol monophosphatase identified as a galactose 1-phosphatase."
      Parthasarathy R. , Parthasarathy L. , Vadnal R.
      Brain Res.778:99-106(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;COFACTOR;ENZYME REGULATION;SUBUNIT
    4. 4.
      "High-resolution structure of myo-inositol monophosphatase, the putative target of lithium therapy."
      Gill R. , Mohammed F. , Badyal R. , Coates L. , Erskine P. , Thompson D. , Cooper J. , Gore M. , Wood S.
      Acta Crystallogr. D61:545-555(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS) IN COMPLEX WITH MAGNESIUM IONS;COFACTOR;SUBUNIT
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