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Index > Protein center > INHBB(Gene name) > Human
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  • INHBB (Gene name),
  • Inhibin beta B chain (Protein name ),  INHBB_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    INHBB;
    Protein name:
    Inhibin beta B chain;
    Alternative:
    Activin beta-B chain;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3.
    Function:
    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    407
    Sequence:
    50:
    MDGLPGRALG | AACLLLLAAG | WLGPEAWGSP | TPPPTPAAPP | PPPPPGSPGG | 
    100:
    SQDTCTSCGG | FRRPEELGRV | DGDFLEAVKR | HILSRLQMRG | RPNITHAVPK | 
    150:
    AAMVTALRKL | HAGKVREDGR | VEIPHLDGHA | SPGADGQERV | SEIISFAETD | 
    200:
    GLASSRVRLY | FFISNEGNQN | LFVVQASLWL | YLKLLPYVLE | KGSRRKVRVK | 
    250:
    VYFQEQGHGD | RWNMVEKRVD | LKRSGWHTFP | LTEAIQALFE | RGERRLNLDV | 
    300:
    QCDSCQELAV | VPVFVDPGEE | SHRPFVVVQA | RLGDSRHRIR | KRGLECDGRT | 
    350:
    NLCCRQQFFI | DFRLIGWNDW | IIAPTGYYGN | YCEGSCPAYL | AGVPGSASSF | 
    400:
    HTAVVNQYRM | RGLNPGTVNS | CCIPTKLSTM | SMLYFDDEYN | IVKRDVPNMI | 
    407:
    VEECGCA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    KEGG:
    UniGene:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Inhibin beta B chain
    Cat.:
    E1762h
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    Packing:
    96T
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    ELISA Kit for Human Inhibin beta B chain
    Cat.:
    E1762b
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    Packing:
    96T
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    ELISA Kit for Human Inhibin beta B chain
    Cat.:
    E1762c
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    96T
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    ELISA Kit for Human Inhibin beta B chain
    Cat.:
    E1762r
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    MSDS:
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    96T
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    ELISA Kit for Human Inhibin beta B chain
    Cat.:
    E1762m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Inhibin beta B chain
    Cat.:
    E1762p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Inhibin beta B chain
    Cat.:
    U1762r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Inhibin beta B chain
    Cat.:
    U1762c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Inhibin beta B chain
    Cat.:
    U1762b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Inhibin beta B chain
    Cat.:
    U1762h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Inhibin beta B chain
    Cat.:
    U1762p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Inhibin beta B chain
    Cat.:
    U1762m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Inhibin beta B chain
    Cat.:
    P1762Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Inhibin beta B chain
    Polyclonal Antibody for Human Inhibin beta B chain
    Polyclonal Antibody for Human Inhibin beta B chain
    Cat.:
    P1762Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Inhibin beta B chain
    Cat.:
    P1762Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Inhibin beta B chain
    Monoclonal Antibody for Human Inhibin beta B chain
    Monoclonal Antibody for Human Inhibin beta B chain
    Monoclonal Antibody for Human Inhibin beta B chain
    Monoclonal Antibody for Human Inhibin beta B chain
    Monoclonal Antibody for Human Inhibin beta B chain
    Monoclonal Antibody for Human Inhibin beta B chain
    Protein for Human Inhibin beta B chain
    Protein for Human Inhibin beta B chain
    Protein for Human Inhibin beta B chain
    Protein for Human Inhibin beta B chain
    Protein for Human Inhibin beta B chain
    Protein for Human Inhibin beta B chain

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    Linearity
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    References
    1. 1.
      "Activin B: precursor sequences, genomic structure and in vitro activities."
      Mason A.J. , Berkemeier L.M. , Schmelzer C.H. , Schwall R.H.
      Mol. Endocrinol.3:1352-1358(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    5. 5.
      "Characterization and regulation of testicular inhibin beta-subunit mRNA."
      Feng Z.M. , Bardin C.W. , Chen C.L.
      Mol. Endocrinol.3:939-948(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 22-407
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 55-407
    7. 7.
      "Purification and characterization of recombinant human activin B."
      Schmelzer C.H. , Burton L.E. , Tamony C.M. , Schwall R.H. , Mason A.J. , Liegeois N.
      Biochim. Biophys. Acta1039:135-141(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 293-307
    8. 8.
      "Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG)."
      Schneyer A. , Schoen A. , Quigg A. , Sidis Y.
      Endocrinology144:1671-1674(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FST AND FSTL3
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