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Index > Protein center > Insm1(Gene name) > Mouse
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  • Insm1 (Gene name),
  • Insulinoma-associated protein 1 (Protein name ),  INSM1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Insm1(Ia1);
    Protein name:
    Insulinoma-associated protein 1;
    Alternative:
    Zinc finger protein IA-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May be associated with the transformation of neuroendocrine cells.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    521
    Sequence:
    50:
    MPRGFLVKRS | KKSTPVSYRV | RGGEDSDRAL | LLSPGCGGAR | AEPPVPSPGP | 
    100:
    LPPPPPPALA | ERAHAALAAA | LACAPGPPPP | PPPGPRAAHF | GNPEAAHPAP | 
    150:
    LYSPTRPVSR | EHEKHKYFER | SFNLGSPVSA | ESFPTPAALL | AGGGSGANGA | 
    200:
    GGGGGGTCGG | DALLFAPAEL | KMGTAFSAGA | EAARGPGTGP | PLSPAAALRP | 
    250:
    PGKRPAPPAA | VATEPPAKAA | KAPSAKKPKA | IRKLHFEDEV | TTSPVLGLKI | 
    300:
    KEGPVEAPRG | RAGGATRPLG | EFICQLCKEE | YADPFALAQH | KCSRIVRVEY | 
    350:
    RCPECAKVFS | CPANLASHRR | WHKPRPVPAA | ARAPEPEAAT | RAEAREAAGG | 
    400:
    GSSDRDTPSP | GGVSESGSED | GLYECHHCAK | KFRRQAYLRK | HLLAHHQALQ | 
    450:
    AKGAPPPPPP | PPPPAEDILA | FYAGPDEKAP | QEASGDGEAA | GVLGLSATAQ | 
    500:
    CHLCPVCGET | FPSKGAQERH | LRLLHAAQVF | PCKYCPATFY | SSPGLTRHIN | 
    521:
    KCHPSENRQV | ILLQVPVRPA | C
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Insulinoma-associated protein 1
    ELISA Kit for Mouse Insulinoma-associated protein 1
    ELISA Kit for Mouse Insulinoma-associated protein 1
    CLIA Kit for Mouse Insulinoma-associated protein 1
    CLIA Kit for Mouse Insulinoma-associated protein 1
    CLIA Kit for Mouse Insulinoma-associated protein 1
    Polyclonal Antibody for Mouse Insulinoma-associated protein 1
    Polyclonal Antibody for Mouse Insulinoma-associated protein 1
    Polyclonal Antibody for Mouse Insulinoma-associated protein 1
    Monoclonal Antibody for Mouse Insulinoma-associated protein 1
    Monoclonal Antibody for Mouse Insulinoma-associated protein 1
    Monoclonal Antibody for Mouse Insulinoma-associated protein 1
    Protein for Mouse Insulinoma-associated protein 1
    Protein for Mouse Insulinoma-associated protein 1
    Protein for Mouse Insulinoma-associated protein 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The zinc-finger transcription factor INSM1 is expressed during embryo development and interacts with the Cbl-associated protein."
      Xie J. , Cai T. , Zhang H. , Lan M.S. , Notkins A.L.
      Genomics80:54-61(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH SORBS1;DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION
    2. 2.
      "NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system."
      Breslin M.B. , Zhu M. , Lan M.S.
      J. Biol. Chem.278:38991-38997(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE
    5. 5.
      "The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells."
      Gierl M.S. , Karoulias N. , Wende H. , Strehle M. , Birchmeier C.
      Genes Dev.20:2465-2478(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    6. 6.
      "Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage."
      Wildner H. , Gierl M.S. , Strehle M. , Pla P. , Birchmeier C.
      Development135:473-481(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    7. 7.
      "Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex."
      Farkas L.M. , Haffner C. , Giger T. , Khaitovich P. , Nowick K. , Birchmeier C. , Paabo S. , Huttner W.B.
      Neuron60:40-55(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    8. 8.
      "Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors."
      Welcker J.E. , Hernandez-Miranda L.R. , Paul F.E. , Jia S. , Ivanov A. , Selbach M. , Birchmeier C.
      Development140:4947-4958(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;INTERACTION WITH HDAC1; HDAC2; KDM1A AND RCOR1
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