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Index > Protein center > INTS10(Gene name) > Human
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  • INTS10 (Gene name),
  • Integrator complex subunit 10 (Protein name ),  INT10_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    INTS10(C8orf35);
    Protein name:
    Integrator complex subunit 10(Int10);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12. Interacts with POLR2A.
    Function:
    Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    710
    Sequence:
    50:
    MSAQGDCEFL | VQRARELVPQ | DLWAAKAWLI | TARSLYPADF | NIQYEMYTIE | 
    100:
    RNAERTATAG | RLLYDMFVNF | PDQPVVWREI | SIITSALRND | SQDKQTQFLR | 
    150:
    SLFETLPGRV | QCEMLLKVTE | QCFNTLERSE | MLLLLLRRFP | ETVVQHGVGL | 
    200:
    GEALLEAETI | EEQESPVNCF | RKLFVCDVLP | LIINNHDVRL | PANLLYKYLN | 
    250:
    KAAEFYINYV | TRSTQIENQH | QGAQDTSDLM | SPSKRSSQKY | IIEGLTEKSS | 
    300:
    QIVDPWERLF | KILNVVGMRC | EWQMDKGRRS | YGDILHRMKD | LCRYMNNFDS | 
    350:
    EAHAKYKNQV | VYSTMLVFFK | NAFQYVNSIQ | PSLFQGPNAP | SQVPLVLLED | 
    400:
    VSNVYGDVEI | DRNKHIHKKR | KLAEGREKTM | SSDDEDCSAK | GRNRHIVVNK | 
    450:
    AELANSTEVL | ESFKLARESW | ELLYSLEFLD | KEFTRICLAW | KTDTWLWLRI | 
    500:
    FLTDMIIYQG | QYKKAIASLH | HLAALQGSIS | QPQITGQGTL | EHQRALIQLA | 
    550:
    TCHFALGEYR | MTCEKVLDLM | CYMVLPIQDG | GKSQEEPSKV | KPKFRKGSDL | 
    600:
    KLLPCTSKAI | MPYCLHLMLA | CFKLRAFTDN | RDDMALGHVI | VLLQQEWPRG | 
    650:
    ENLFLKAVNK | ICQQGNFQYE | NFFNYVTNID | MLEEFAYLRT | QEGGKIHLEL | 
    700:
    LPNQGMLIKH | HTVTRGITKG | VKEDFRLAME | RQVSRCGENL | MVVLHRFCIN | 
    710:
    EKILLLQTLT | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    MIM:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Int10
    ELISA Kit for Human Int10
    ELISA Kit for Human Int10
    CLIA Kit for Human Int10
    CLIA Kit for Human Int10
    CLIA Kit for Human Int10
    Polyclonal Antibody for Human Int10
    Polyclonal Antibody for Human Int10
    Polyclonal Antibody for Human Int10
    Monoclonal Antibody for Human Int10
    Monoclonal Antibody for Human Int10
    Monoclonal Antibody for Human Int10
    Protein for Human Int10
    Protein for Human Int10
    Protein for Human Int10

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    Precision
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Teratocarcinoma.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 74-710
      tissue: Lung.
      tissue: Neuroblastoma.
    3. 3.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 114-710
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 377-710
      tissue: Lymph node.
    5. 5.
      "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II."
      Baillat D. , Hakimi M.-A. , Naeaer A.M. , Shilatifard A. , Cooch N. , Shiekhattar R.
      Cell123:265-276(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE INTEGRATOR COMPLEX;SUBCELLULAR LOCATION
    6. 6.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-231;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    8. 8.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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