Gene name:
Ints2 (Kiaa1287) ;
Protein name:
Integrator complex subunit 2 (Int2) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12.
Function:
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
Subcellular Location:
Nucleus membrane
Single-pass membrane protein
Protein Attributes:
50:
MTPEGTGLQF | VSPFAFEAMQ | KVDVVRLASL | SDPELRLLLP | CLVRMALCAP |
100:
ADQSQSWAQD | KKLILRLLSG | VEAVNSIVAL | LSVDFHALEQ | DASKEQQLRH |
150:
KLGGGSGESI | LVSQLQHGLT | LEFEHSDSPR | RLRLVLSELL | AIMNKVSECN |
200:
GEFFFKSSEL | FESAVYLEEA | ADVLCILQAE | LPSLLPIVDV | AEALLRVRNG |
250:
AWFLCLLVAN | VPDSFNEVCR | GLIKNGERQD | EESLGGRRRT | DALRFLCRMN |
300:
PSQALKVRGM | VVEECHLPGL | GVALTLDHTK | TEACEDGVSD | LVCFVSGLLL |
350:
GTNAKVRTWF | GTFIRNGQQR | KRETSGSVLW | QMRRQLLLEL | MGILPTVRST |
400:
RIVEEADVEM | EPTVSVYSGL | KEEHVVKASA | LLRLYCALMG | IAGLKPTEEE |
450:
AEQLLQLMTS | RPPATPAGVR | FVSLSFCMLL | AFSTLVSTPE | QEQLMVLWLS |
500:
WMIKEEAYFE | STSGVSASFG | EMLLLVAMYF | HSNQLSAIID | LVCSTLGMKI |
550:
VIKPSSLSRM | KTIFTQEIFT | EQVVTAHAVR | VPVTSNLSAN | ITGFLPIHCI |
600:
YQLLRSRSFT | KHKVSIKDWI | YRQLCETSTP | LHPQLLPLID | VYINSILTPA |
650:
SKSNPEATNQ | PVTEQEILNL | FQEVIGGDSV | RLTQRFSITA | QLLVLYYILS |
700:
YEEALLANTK | TLASMQRKPK | SYSSSLMDQI | PIKFLIRQAQ | GLQQELGGLH |
750:
SALLRLLATN | YPHLCIVDDW | ICEEEITGTD | ALLRRMLLTS | NAKTHSPKQL |
800:
QEAFSAVPVS | HTQVMQIMEH | LTLLSASELI | PYAEVLTSNM | NQLLNSGVPR |
850:
RILQTVNKLW | MVLNTVMPRR | LWVMTVNALQ | PSIKFIRQQK | YTQNDLMIDP |
900:
LIVLRCDRRV | HRCPPLMDVT | LHMLNGYLLA | SKAYLSAHLK | ETAEQDRPSP |
950:
NNTVGLVGQT | DAPEVTREEL | KNALLAAQDS | AAVQILLEIC | LPTEEEKAKG |
1000:
ANSDISLRNT | QGVTTISTPS | KETEEGEDNL | LCNLREVQCL | ICCLLHQMYI |
1050:
ADPNIAKLVH | FQGYPCELLP | LTVAGIPSMH | ICLDFIPELI | AQPELEKQIF |
1100:
AIQLLSHLCI | QYALPKSLSV | ARLAVNVMGT | LLTVLTQAKR | YSFFMPTLPS |
1150:
LVSFCRAFPP | LYEDIMSLLI | QIGQVCASDV | ATQTRDIDPI | ITRLQQIKEK |
1198:
PSGWSQICKD | PSYKNGSRDT | GSMDPDVQLC | HCIESTIIEI | INMSVSGI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Chicken
Polyclonal Antibody for Mouse Int2
Polyclonal Antibody for Mouse Int2
Polyclonal Antibody for Mouse Int2
Monoclonal Antibody for Mouse Int2
Monoclonal Antibody for Mouse Int2
Monoclonal Antibody for Mouse Int2
R&D Technical Data
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Precision
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Recovery
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Linearity
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Embryonic tail .
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain :
C57BL/6J .
tissue :
Vagina .
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PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
B5/EGFP .
tissue :
Brain .
tissue :
Trophoblast stem cell .