Gene name:
INTS4 (MSTP093) ;
Protein name:
Integrator complex subunit 4 (Int4) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12.
Function:
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MAAHLKKRVY | EEFTKVVQPQ | EEIATKKLRL | TKPSKSAALH | IDLCKATSPA |
100:
DALQYLLQFA | RKPVEAESVE | GVVRILLEHY | YKENDPSVRL | KIASLLGLLS |
150:
KTAGFSPDCI | MDDAINILQN | EKSHQVLAQL | LDTLLAIGTK | LPENQAIQMR |
200:
LVDVACKHLT | DTSHGVRNKC | LQLLGNLGSL | EKSVTKDAEG | LAARDVQKII |
250:
GDYFSDQDPR | VRTAAIKAML | QLHERGLKLH | QTIYNQACKL | LSDDYEQVRS |
300:
AAVQLIWVVS | QLYPESIVPI | PSSNEEIRLV | DDAFGKICHM | VSDGSWVVRV |
350:
QAAKLLGSME | QVSSHFLEQT | LDKKLMSDLR | RKRTAHERAK | ELYSSGEFSS |
400:
GRKWGDDAPK | EEVDTGAVNL | IESGACGAFV | HGLEDEMYEV | RIAAVEALCM |
450:
LAQSSPSFAE | KCLDFLVDMF | NDEIEEVRLQ | SIHTMRKISN | NITLREDQLD |
500:
TVLAVLEDSS | RDIREALHEL | LCCTNVSTKE | GIHLALVELL | KNLTKYPTDR |
550:
DSIWKCLKFL | GSRHPTLVLP | LVPELLSTHP | FFDTAEPDMD | DPAYIAVLVL |
600:
IFNAAKTCPT | MPALFSDHTF | RHYAYLRDSL | SHLVPALRLP | GRKLVSSAVS |
650:
PSIIPQEDPS | QQFLQQSLER | VYSLQHLDPQ | GAQELLEFTI | RDLQRLGELQ |
700:
SELAGVADFS | ATYLRCQLLL | IKALQEKLWN | VAAPLYLKQS | DLASAAAKQI |
750:
MEETYKMEFM | YSGVENKQVV | IIHHMRLQAK | ALQLIVTART | TRGLDPLFGM |
800:
CEKFLQEVDF | FQRYFIADLP | HLQDSFVDKL | LDLMPRLMTS | KPAEVVKILQ |
850:
TMLRQSAFLH | LPLPEQIHKA | SATIIEPAGE | SDNPLRFTSG | LVVALDVDAT |
900:
LEHVQDPQNT | VKVQVLYPDG | QAQMIHPKPA | DFRNPGPGRH | RLITQVYLSH |
950:
TAWTEACQVE | VRLLLAYNSS | ARIPKCPWME | GGEMSPQVET | SIEGTIPFSK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Polyclonal Antibody for Human Int4
Polyclonal Antibody for Human Int4
Monoclonal Antibody for Human Int4
Monoclonal Antibody for Human Int4
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
Sheng H.
,
Qin B.M.
,
Liu Y.Q.
,
Zhao B.
,
Liu B.
,
Wang X.Y.
,
Zhang Q.
,
Song L.
,
Gao Y.
,
Zhang C.L.
,
Ye J.
,
Ji X.J.
,
Liu B.H.
,
Lu H.
,
Xu H.S.
,
Chen J.Z.
,
Cai M.Q.
,
Zheng W.Y.
,
Teng C.Y.
,
Liu Q.
,
Yu L.T.
,
Lin J.
,
Gong J.
,
Zhang A.M.
,
Gao R.L.
,
Hui R.T.
more...
Submitted (1999-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
tissue :
Aorta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 174-963 (ISOFORM 1)
tissue :
Brain .
tissue :
Muscle .
tissue :
Ovary .
tissue :
Uterus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION (ISOFORM 1);IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE INTEGRATOR COMPLEX