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Index > Protein center > IRF2(Gene name) > Chicken
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  • IRF2 (Gene name),
  • Interferon regulatory factor 2 (Protein name ),  IRF2_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IRF2;
    Protein name:
    Interferon regulatory factor 2(IRF-2);
    Alternative:

    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Interacts with CREBBP in growing cells; the interaction acetylates IRF2 and regulates IRF2-dependent H4 promoter activity.
    Function:
    Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    348
    Sequence:
    50:
    MPVERMRMRP | WLEEQINSNT | IPGLKWINKE | KKIFQIPWMH | AARHGWDVEK | 
    100:
    DAPLFRNWAI | HTGKYQSGVD | KPDPKTWKAN | FRCAMNSLPD | IEEVKDKSIK | 
    150:
    KGNNAFRVYR | MLPLSERPSK | KGKKTKSEKD | DKFKQIKQEP | VESSFGINGL | 
    200:
    NDVTSDYFLS | SSIKNEVDST | VNIVVVGQPH | LDGSSEEQVI | VANPPDVCQV | 
    250:
    VEVTTESDEQ | PLSMSQLYPL | QISPVSSYAE | SETTDSVPSD | EENAEGRLHW | 
    300:
    QKKNIEGKQY | LSNLGMRNTS | HMLPSMATFV | ANKPDLQVTI | KEESCPLPYN | 
    348:
    SSWPPFPDIP | LPQVVSTAST | SSSRPDRETR | ASVIKKTSDI | TQSRVKSC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken IRF-2
    ELISA Kit for Chicken IRF-2
    ELISA Kit for Chicken IRF-2
    CLIA Kit for Chicken IRF-2
    CLIA Kit for Chicken IRF-2
    CLIA Kit for Chicken IRF-2
    Polyclonal Antibody for Chicken IRF-2
    Polyclonal Antibody for Chicken IRF-2
    Polyclonal Antibody for Chicken IRF-2
    Monoclonal Antibody for Chicken IRF-2
    Monoclonal Antibody for Chicken IRF-2
    Monoclonal Antibody for Chicken IRF-2
    Protein for Chicken IRF-2
    Protein for Chicken IRF-2
    Protein for Chicken IRF-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of chicken interferon regulatory factor-2 (IRF-2) cDNA: expression and mapping of the IRF-2 gene."
      Marienfeld R. , Nanda I. , Zoeller B. , Schmid M. , Rebbert M. , Jungwirth C.
      J. Interferon Cytokine Res.17:219-227(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Embryo.
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