Protein name:
ATP-sensitive inward rectifier potassium channel 10 ;
Alternative:
Inward rectifier K(+) channel Kir1.2 ;ATP-dependent inwardly rectifying potassium channel Kir4.1 ;Potassium channel, inwardly rectifying subfamily J member 10 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Seems to form heterodimer with Kir5.1/KCNJ16. Interacts with INADL.
Function:
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MTSVAKVYYS | QTTQTESRPL | MGPGIRRRRV | LTKDGRSNVR | MEHIADKRFL |
100:
YLKDLWTTFI | DMQWRYKLLL | FSATFAGTWF | LFGVVWYLVA | VAHGDLLELD |
150:
PPANHTPCVV | QVHTLTGAFL | FSLESQTTIG | YGFRYISEEC | PLAIVLLIAQ |
200:
LVLTTILEIF | ITGTFLAKIA | RPKKRAETIR | FSQHAVVASH | NGKPCLMIRV |
250:
ANMRKSLLIG | CQVTGKLLQT | HQTKEGENIR | LNQVNVTFQV | DTASDSPFLI |
300:
LPLTFYHVVD | ETSPLKDLPL | RSGEGDFELV | LILSGTVEST | SATCQVRTSY |
350:
LPEEILWGYE | FTPAISLSAS | GKYIADFSLF | DQVVKVASPS | GLRDSTVRYG |
379:
DPEKLKLEES | LREQAEKEGS | ALSVRISNV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Human ATP-sensitive inward rectifier potassium channel 10
ELISA Kit for Human ATP-sensitive inward rectifier potassium channel 10
ELISA Kit for Human ATP-sensitive inward rectifier potassium channel 10
CLIA Kit for Human ATP-sensitive inward rectifier potassium channel 10
CLIA Kit for Human ATP-sensitive inward rectifier potassium channel 10
CLIA Kit for Human ATP-sensitive inward rectifier potassium channel 10
Polyclonal Antibody for Human ATP-sensitive inward rectifier potassium channel 10
Polyclonal Antibody for Human ATP-sensitive inward rectifier potassium channel 10
Polyclonal Antibody for Human ATP-sensitive inward rectifier potassium channel 10
Monoclonal Antibody for Human ATP-sensitive inward rectifier potassium channel 10
Monoclonal Antibody for Human ATP-sensitive inward rectifier potassium channel 10
Monoclonal Antibody for Human ATP-sensitive inward rectifier potassium channel 10
Protein for Human ATP-sensitive inward rectifier potassium channel 10
Protein for Human ATP-sensitive inward rectifier potassium channel 10
Protein for Human ATP-sensitive inward rectifier potassium channel 10
R&D Technical Data
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Precision
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Recovery
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Linearity
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