KCNJ2 ELISA Kit for Dog(Canis familiaris) | EIAab.comKCNJ2 ELISA Kit for Dog(Canis familiaris)

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Index > Protein center > KCNJ2(Gene name) > Dog

KCNJ2 (Gene name),

Inward rectifier potassium channel 2 (Protein name ), IRK2_CANFA from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

KCNJ2(IRK1);

Protein name:

Inward rectifier potassium channel 2;

Alternative:

Inward rectifier K(+) channel Kir2.1(IRK-1);Cardiac inward rectifier potassium channel;Potassium channel, inwardly rectifying subfamily J member 2;

Organism:

Dog (Canis familiarisCanis lupus familiaris).

General Annotation

Sub Unit:

Homomultimeric and heteromultimeric association with Kir2.3, resulting in an enhanced G-protein-induced current. Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking.

Function:

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked by external barium or cesium.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

427

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