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Index > Protein center > Kcnj2(Gene name) > Mouse
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  • Kcnj2 (Gene name),
  • Inward rectifier potassium channel 2 (Protein name ),  IRK2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Kcnj2(Irk1);
    Protein name:
    Inward rectifier potassium channel 2;
    Alternative:
    Potassium channel, inwardly rectifying subfamily J member 2;Inward rectifier K(+) channel Kir2.1(IRK-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homomultimeric and heteromultimeric association with Kir2.3, resulting in an enhanced G-protein-induced current. Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking.
    Function:
    Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    428
    Sequence:
    50:
    MGSVRTNRYS | IVSSEEDGMK | LATMAVANGF | GNGKSKVHTR | QQCRSRFVKK | 
    100:
    DGHCNVQFIN | VGEKGQRYLA | DIFTTCVDIR | WRWMLVIFCL | AFVLSWLFFG | 
    150:
    CVFWLIALLH | GDLDTSKVSK | ACVSEVNSFT | AAFLFSIETQ | TTIGYGFRCV | 
    200:
    TDECPIAVFM | VVFQSIVGCI | IDAFIIGAVM | AKMAKPKKRN | ETLVFSHNAV | 
    250:
    IAMRDGKLCL | MWRVGNLRKS | HLVEAHVRAQ | LLKSRITSEG | EYIPLDQIDI | 
    300:
    NVGFDSGIDR | IFLVSPITIV | HEIDEDSPLY | DLSKQDIDNA | DFEIVVILEG | 
    350:
    MVEATAMTTQ | CRSSYLANEI | LWGHRYEPVL | FEEKHYYKVD | YSRFHKTYEV | 
    400:
    PNTPLCSARD | LAEKKYILSN | ANSFCYENEV | ALTSKEEEED | SENGVPESTS | 
    428:
    TDSPPGIDLH | NQASVPLEPR | PLRRESEI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    KEGG:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    ELISA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    CLIA Kit for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Polyclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Monoclonal Antibody for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2
    Protein for Mouse Inward rectifier potassium channel 2

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