Protein name:
Integrin alpha-X ;
Alternative:
Leu M5 ;CD11 antigen-like family member C ;Leukocyte adhesion receptor p150,95 ;Leukocyte adhesion glycoprotein p150,95 alpha chain ;
CD:
CD11c ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2.
Function:
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MTRTRAALLL | FTALATSLGF | NLDTEELTAF | RVDSAGFGDS | VVQYANSWVV |
100:
VGAPQKITAA | NQTGGLYQCG | YSTGACEPIG | LQVPPEAVNM | SLGLSLASTT |
150:
SPSQLLACGP | TVHHECGRNM | YLTGLCFLLG | PTQLTQRLPV | SRQECPRQEQ |
200:
DIVFLIDGSG | SISSRNFATM | MNFVRAVISQ | FQRPSTQFSL | MQFSNKFQTH |
250:
FTFEEFRRSS | NPLSLLASVH | QLQGFTYTAT | AIQNVVHRLF | HASYGARRDA |
300:
AKILIVITDG | KKEGDSLDYK | DVIPMADAAG | IIRYAIGVGL | AFQNRNSWKE |
350:
LNDIASKPSQ | EHIFKVEDFD | ALKDIQNQLK | EKIFAIEGTE | TTSSSSFELE |
400:
MAQEGFSAVF | TPDGPVLGAV | GSFTWSGGAF | LYPPNMSPTF | INMSQENVDM |
450:
RDSYLGYSTE | LALWKGVQSL | VLGAPRYQHT | GKAVIFTQVS | RQWRMKAEVT |
500:
GTQIGSYFGA | SLCSVDVDSD | GSTDLVLIGA | PHYYEQTRGG | QVSVCPLPRG |
550:
WRRWWCDAVL | YGEQGHPWGR | FGAALTVLGD | VNGDKLTDVV | IGAPGEEENR |
600:
GAVYLFHGVL | GPSISPSHSQ | RIAGSQLSSR | LQYFGQALSG | GQDLTQDGLV |
650:
DLAVGARGQV | LLLRTRPVLW | VGVSMQFIPA | EIPRSAFECR | EQVVSEQTLV |
700:
QSNICLYIDK | RSKNLLGSRD | LQSSVTLDLA | LDPGRLSPRA | TFQETKNRSL |
750:
SRVRVLGLKA | HCENFNLLLP | SCVEDSVTPI | TLRLNFTLVG | KPLLAFRNLR |
800:
PMLAADAQRY | FTASLPFEKN | CGADHICQDN | LGISFSFPGL | KSLLVGSNLE |
850:
LNAEVMVWND | GEDSYGTTIT | FSHPAGLSYR | YVAEGQKQGQ | LRSLHLTCDS |
900:
APVGSQGTWS | TSCRINHLIF | RGGAQITFLA | TFDVSPKAVL | GDRLLLTANV |
950:
SSENNTPRTS | KTTFQLELPV | KYAVYTVVSS | HEQFTKYLNF | SESEEKESHV |
1000:
AMHRYQVNNL | GQRDLPVSIN | FWVPVELNQE | AVWMDVEVSH | PQNPSLRCSS |
1050:
EKIAPPASDF | LAHIQKNPVL | DCSIAGCLRF | RCDVPSFSVQ | EELDFTLKGN |
1100:
LSFGWVRQIL | QKKVSVVSVA | EITFDTSVYS | QLPGQEAFMR | AQTTTVLEKY |
1150:
KVHNPTPLIV | GSSIGGLLLL | ALITAVLYKV | GFFKRQYKEM | MEEANGQIAP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Integrin alpha-X
ELISA Kit for Human Integrin alpha-X
CLIA Kit for Human Integrin alpha-X
CLIA Kit for Human Integrin alpha-X
Polyclonal Antibody for Human Integrin alpha-X
Polyclonal Antibody for Human Integrin alpha-X
Monoclonal Antibody for Human Integrin alpha-X
Monoclonal Antibody for Human Integrin alpha-X
Protein for Human Integrin alpha-X
Protein for Human Integrin alpha-X
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT THR-251
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LEU-201 AND THR-251
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT LYS-547
tissue :
Blood .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 20-43
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-899
tissue :
Liver .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF 20-1103 IN COMPLEX WITH ITGB2;GLYCOSYLATION AT ASN-61; ASN-392; ASN-697; ASN-735 AND ASN-899;DISULFIDE BONDS;METAL-BINDING SITES;SUBUNIT
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 1129-1163
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Am. J. Hum. Genet.89:162-167(2011)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT VAL-1012