Protein name:
Inositol 1,4,5-trisphosphate receptor type 2 ;
Alternative:
Type 2 inositol 1,4,5-trisphosphate receptor (Type 2 InsP3 receptor) ;IP3 receptor isoform 2 (IP3R 2;InsP3R2) ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homotetramer (By similarity). Interacts with CABP1.
Function:
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Cytoplasmic vesicle
secretory vesicle membrane
Multi-pass membrane protein
Endoplasmic reticulum and secretory granules.
Protein Attributes:
50:
MSDKMSSFLY | IGDIVSLYAE | GSVNGFINTL | GLVDDRCVVH | PEAGDLANPP |
100:
KKFRDCLFKV | CPMNRYSAQK | QYWKAKQAKQ | GNHTEAALLK | KLQHAAELEQ |
150:
KQNESENKKL | LGEIVKYSNV | IQLLHIKSNK | YLTVNKRLPA | LLEKNAMRVS |
200:
LDAAGNEGSW | FYIHPFWKLR | SEGDNIVVGG | KVVLMPVNAG | QPLHASNIEL |
250:
LDNPGCKEVN | AVNCNTSWKI | TLFMKYSSYR | EDVLKGGDVV | RLFHAEQEKF |
300:
LTCDEYEKKQ | HIFLRTTLRQ | SATSATSSKA | LWEIEVVHHD | PCRGGAGQWN |
350:
SLFRFKHLAT | GNYLAAELNP | DYRDAQNEGK | NVRDGDLPAS | KKKRQAGEKI |
400:
MYTLVSVPHG | NDIASLFELD | ATTLQRADCL | VPRNSYVRLR | HLCTNTWVTS |
450:
TSIPIDTDEE | RPVMLKIGTC | QTKEDKEAFA | IVSVPPSEVR | DLDFANDANK |
500:
VLATTVKKLE | NGTITQNERR | FVTKLLEDLI | FFVADVPNNG | QDVLDVLITK |
550:
PNRERQKLMR | EQNILAQVFG | ILKAPFKEKA | GEGSMLRLED | LGDQRYAPYK |
600:
YMLRLCYRVL | GHSQQDYRKN | QEYIAKNFCV | MQSQIGYDIL | AEDTITALLH |
650:
NNRKLLEKHI | TAKEIETFVS | LLRRNREPRF | LDYLSDLCVS | NTTAIPVTQE |
700:
LICKFMLSPG | NADILIQTKL | VSMQGDNPME | SAILSDDIDE | EEVWLYWIDS |
750:
NKEPHGKAIR | HLAQEAKEGT | KADLEVLTYY | RYQLNLFARM | CLDRQYLAIN |
800:
QISTQLSVDL | ILRCMSDESL | PFDLRASFCR | LMLHMHVDRD | PQESVVPVRY |
850:
ARLWTEIPTK | ITIHEYDSIT | DSSRNDMKRK | FALTMEFVEE | YLKEVVNQPF |
900:
PFGDKEKNKL | TFEVVHLARN | LIYFGFYSFS | ELLRLTRTLL | AILDIVQAPM |
950:
SSYFERLSKF | QDGGNNVMRT | IHGVGEMMTQ | MVLSRGSIFP | MSVPDIQPSL |
1000:
HPSKQGSPTD | HEDVTVMDTK | LKIIEILQFI | LSVRLDYGIS | YMLSIYKKEF |
1050:
GENNGNAEMS | TNGSPDTLLP | SAIVPDIDEI | AAQAETMFAG | RKEKNPVQLD |
1100:
DEGGRTFLRV | LIHLIMHDYP | PLLSGALQLL | FKHFSQRAEV | LQAFKQVQLL |
1150:
VSNQDVDNYK | QIKADLDQLR | LTVEKSELWV | EKSSSYENGE | MGENQVKGGE |
1200:
EPIEDSNILS | PVQDGTKKPQ | IDSNKSNNYR | IVKEILIRLS | KLCVQNKKCR |
1250:
NQHQRLLKNM | GAHSVVLDLL | QIPYEKNDEK | MNEVMNLAHT | FLQNFCRGNP |
1300:
QNQVLLHKHL | NLFLTPGLLE | AETMRHIFMN | NYHLCNEISE | RVVQHFVHCI |
1350:
ETHGRHVEYL | RFLQTIVKAD | GKYVKKCQDM | VMTELINGGE | DVLIFYNDRA |
1400:
SFPILLHMMC | SERDRGDESG | PLAYHITLVE | LLAACTEGKN | VYTEIKCNSL |
1450:
LPLDDIVRVV | THDDCIPEVK | IAYVNFVNHC | YVDTEVEMKE | IYTSNHIWKL |
1500:
FENFLVDMAR | VCNTTTDRKH | ADTFLEKCVT | ESIMNIVSGF | FNSPFSDNST |
1550:
SLQTHQPVFI | QLLQSAFRIY | NCTWPNPAQK | ASVESCIRTL | AEVAKNRGIA |
1600:
IPVDLDSQVN | TLFLKSHSNM | VQRAAMGWRL | SARSGPRFKE | ALGGPSWDYR |
1650:
NIIEKLQDVV | ASLEQQFSPM | MQAEFSVLVD | VLYSPELLFP | EGSDARIRCG |
1700:
AFMSKLINHT | KKLMEKEEKL | CIKILQTLRE | MLEKKDSFVE | EGNTLRKILL |
1750:
NRYFKGDYGV | SINGHLSGTY | CKTAQVGGSF | SGQDSDKMGI | SMSDIQCLLD |
1800:
KEGASELVID | VIVNTKNDRI | FSEGILLGIA | LLEGGNTQTQ | YSFYQQLHEQ |
1850:
KKSEKFFKVL | YDRMKAAQKE | IRSTVTVNTI | DLGNKKRDDD | TELMTSGPRM |
1900:
RVRDSSLHLK | EGMKGQLTEA | SSATSKAYCV | YRREMDPEID | IMCAGPEAGN |
1950:
AEDRSTEEVT | MSPAIAIMQP | ISRFLQLLCE | NHNRELQHFL | RNQNNKTNYN |
2000:
LVCETLQFLD | CICGSTTGGL | GLLGLYINEK | NVVLVNQTLE | SLTEYCQGPC |
2050:
HENQTCIATH | ESNGIDIIIA | LILNDINPLG | KYRMDLVLQL | KNNAPKLLLA |
2100:
IMESRHDSEN | AERILFNMRP | RELVDVMKNA | YNQGLECDHG | DDEGGDDDVS |
2150:
PKDVGHNIYI | LAHQLARHNK | LLQQMLKPGS | DPDDGDEALK | YYANHTAQIE |
2200:
IVRHDRTMEQ | IVFPVPNICE | YLTRESKCRV | FNTTERDEQG | SKVNDFFQQT |
2250:
EDLYNEMKWQ | KKIRSNPALF | WFSRHISLWG | SISFNLAVFI | NLAVALFYPF |
2300:
GDDGDEGTLS | PMFSILLWIA | VAICTSMLFF | FSKPVGIRPF | LVSVMLRSIY |
2350:
TIGLGPTLIL | LGAANLCNKI | VFLVSFVGNR | GTFTRGYRAV | ILDMAFLYHV |
2400:
AYVLVCMLGL | FVHEFFYSFL | LFDLVYREET | LLNVIKSVTR | NGRSIILTAV |
2450:
LALILVYLFS | IIGFLFLKDD | FTMEVDRLKN | RTPITGSNAV | PTMTLTSILS |
2500:
TCEKDNCSPT | IPASNTADEE | YEDGIERTCD | TLLMCIVTVL | NQGLRNGGGV |
2550:
GDVLRRPSKD | EPLFAARVVY | DLLFYFIVII | IVLNLIFGVI | IDTFADLRSE |
2600:
KQKKEEILKT | TCFICGLERD | KFDNKTVSFE | EHIKSEHNMW | HYLYFLVLVK |
2650:
VKDPTEYTGP | ESYVAQMIVE | KNLDWFPRMR | AMSLVSSEGD | SEQNEVRNLQ |
2700:
EKLESTMSLV | KQLSSQLAEL | KEQMTEQRKN | KQRLGFLGSN | TPHVNHHMPP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Rat
Mouse
ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2
Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION
tissue :
Adrenal medulla .