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Index > Protein center > ITPR2(Gene name) > Bovine
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  • ITPR2 (Gene name),
  • Inositol 1,4,5-trisphosphate receptor type 2 (Protein name ),  ITPR2_BOVIN from NCBI database.
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  • Gene name:
    ITPR2;
    Protein name:
    Inositol 1,4,5-trisphosphate receptor type 2;
    Alternative:
    Type 2 inositol 1,4,5-trisphosphate receptor(Type 2 InsP3 receptor);IP3 receptor isoform 2(IP3R 2;InsP3R2);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homotetramer (By similarity). Interacts with CABP1.
    Function:
    Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein Cytoplasmic vesicle secretory vesicle membrane Multi-pass membrane protein Endoplasmic reticulum and secretory granules.
    Protein Attributes:
    Sequence length:
    2701
    Sequence:
    50:
    MSDKMSSFLY | IGDIVSLYAE | GSVNGFINTL | GLVDDRCVVH | PEAGDLANPP | 
    100:
    KKFRDCLFKV | CPMNRYSAQK | QYWKAKQAKQ | GNHTEAALLK | KLQHAAELEQ | 
    150:
    KQNESENKKL | LGEIVKYSNV | IQLLHIKSNK | YLTVNKRLPA | LLEKNAMRVS | 
    200:
    LDAAGNEGSW | FYIHPFWKLR | SEGDNIVVGG | KVVLMPVNAG | QPLHASNIEL | 
    250:
    LDNPGCKEVN | AVNCNTSWKI | TLFMKYSSYR | EDVLKGGDVV | RLFHAEQEKF | 
    300:
    LTCDEYEKKQ | HIFLRTTLRQ | SATSATSSKA | LWEIEVVHHD | PCRGGAGQWN | 
    350:
    SLFRFKHLAT | GNYLAAELNP | DYRDAQNEGK | NVRDGDLPAS | KKKRQAGEKI | 
    400:
    MYTLVSVPHG | NDIASLFELD | ATTLQRADCL | VPRNSYVRLR | HLCTNTWVTS | 
    450:
    TSIPIDTDEE | RPVMLKIGTC | QTKEDKEAFA | IVSVPPSEVR | DLDFANDANK | 
    500:
    VLATTVKKLE | NGTITQNERR | FVTKLLEDLI | FFVADVPNNG | QDVLDVLITK | 
    550:
    PNRERQKLMR | EQNILAQVFG | ILKAPFKEKA | GEGSMLRLED | LGDQRYAPYK | 
    600:
    YMLRLCYRVL | GHSQQDYRKN | QEYIAKNFCV | MQSQIGYDIL | AEDTITALLH | 
    650:
    NNRKLLEKHI | TAKEIETFVS | LLRRNREPRF | LDYLSDLCVS | NTTAIPVTQE | 
    700:
    LICKFMLSPG | NADILIQTKL | VSMQGDNPME | SAILSDDIDE | EEVWLYWIDS | 
    750:
    NKEPHGKAIR | HLAQEAKEGT | KADLEVLTYY | RYQLNLFARM | CLDRQYLAIN | 
    800:
    QISTQLSVDL | ILRCMSDESL | PFDLRASFCR | LMLHMHVDRD | PQESVVPVRY | 
    850:
    ARLWTEIPTK | ITIHEYDSIT | DSSRNDMKRK | FALTMEFVEE | YLKEVVNQPF | 
    900:
    PFGDKEKNKL | TFEVVHLARN | LIYFGFYSFS | ELLRLTRTLL | AILDIVQAPM | 
    950:
    SSYFERLSKF | QDGGNNVMRT | IHGVGEMMTQ | MVLSRGSIFP | MSVPDIQPSL | 
    1000:
    HPSKQGSPTD | HEDVTVMDTK | LKIIEILQFI | LSVRLDYGIS | YMLSIYKKEF | 
    1050:
    GENNGNAEMS | TNGSPDTLLP | SAIVPDIDEI | AAQAETMFAG | RKEKNPVQLD | 
    1100:
    DEGGRTFLRV | LIHLIMHDYP | PLLSGALQLL | FKHFSQRAEV | LQAFKQVQLL | 
    1150:
    VSNQDVDNYK | QIKADLDQLR | LTVEKSELWV | EKSSSYENGE | MGENQVKGGE | 
    1200:
    EPIEDSNILS | PVQDGTKKPQ | IDSNKSNNYR | IVKEILIRLS | KLCVQNKKCR | 
    1250:
    NQHQRLLKNM | GAHSVVLDLL | QIPYEKNDEK | MNEVMNLAHT | FLQNFCRGNP | 
    1300:
    QNQVLLHKHL | NLFLTPGLLE | AETMRHIFMN | NYHLCNEISE | RVVQHFVHCI | 
    1350:
    ETHGRHVEYL | RFLQTIVKAD | GKYVKKCQDM | VMTELINGGE | DVLIFYNDRA | 
    1400:
    SFPILLHMMC | SERDRGDESG | PLAYHITLVE | LLAACTEGKN | VYTEIKCNSL | 
    1450:
    LPLDDIVRVV | THDDCIPEVK | IAYVNFVNHC | YVDTEVEMKE | IYTSNHIWKL | 
    1500:
    FENFLVDMAR | VCNTTTDRKH | ADTFLEKCVT | ESIMNIVSGF | FNSPFSDNST | 
    1550:
    SLQTHQPVFI | QLLQSAFRIY | NCTWPNPAQK | ASVESCIRTL | AEVAKNRGIA | 
    1600:
    IPVDLDSQVN | TLFLKSHSNM | VQRAAMGWRL | SARSGPRFKE | ALGGPSWDYR | 
    1650:
    NIIEKLQDVV | ASLEQQFSPM | MQAEFSVLVD | VLYSPELLFP | EGSDARIRCG | 
    1700:
    AFMSKLINHT | KKLMEKEEKL | CIKILQTLRE | MLEKKDSFVE | EGNTLRKILL | 
    1750:
    NRYFKGDYGV | SINGHLSGTY | CKTAQVGGSF | SGQDSDKMGI | SMSDIQCLLD | 
    1800:
    KEGASELVID | VIVNTKNDRI | FSEGILLGIA | LLEGGNTQTQ | YSFYQQLHEQ | 
    1850:
    KKSEKFFKVL | YDRMKAAQKE | IRSTVTVNTI | DLGNKKRDDD | TELMTSGPRM | 
    1900:
    RVRDSSLHLK | EGMKGQLTEA | SSATSKAYCV | YRREMDPEID | IMCAGPEAGN | 
    1950:
    AEDRSTEEVT | MSPAIAIMQP | ISRFLQLLCE | NHNRELQHFL | RNQNNKTNYN | 
    2000:
    LVCETLQFLD | CICGSTTGGL | GLLGLYINEK | NVVLVNQTLE | SLTEYCQGPC | 
    2050:
    HENQTCIATH | ESNGIDIIIA | LILNDINPLG | KYRMDLVLQL | KNNAPKLLLA | 
    2100:
    IMESRHDSEN | AERILFNMRP | RELVDVMKNA | YNQGLECDHG | DDEGGDDDVS | 
    2150:
    PKDVGHNIYI | LAHQLARHNK | LLQQMLKPGS | DPDDGDEALK | YYANHTAQIE | 
    2200:
    IVRHDRTMEQ | IVFPVPNICE | YLTRESKCRV | FNTTERDEQG | SKVNDFFQQT | 
    2250:
    EDLYNEMKWQ | KKIRSNPALF | WFSRHISLWG | SISFNLAVFI | NLAVALFYPF | 
    2300:
    GDDGDEGTLS | PMFSILLWIA | VAICTSMLFF | FSKPVGIRPF | LVSVMLRSIY | 
    2350:
    TIGLGPTLIL | LGAANLCNKI | VFLVSFVGNR | GTFTRGYRAV | ILDMAFLYHV | 
    2400:
    AYVLVCMLGL | FVHEFFYSFL | LFDLVYREET | LLNVIKSVTR | NGRSIILTAV | 
    2450:
    LALILVYLFS | IIGFLFLKDD | FTMEVDRLKN | RTPITGSNAV | PTMTLTSILS | 
    2500:
    TCEKDNCSPT | IPASNTADEE | YEDGIERTCD | TLLMCIVTVL | NQGLRNGGGV | 
    2550:
    GDVLRRPSKD | EPLFAARVVY | DLLFYFIVII | IVLNLIFGVI | IDTFADLRSE | 
    2600:
    KQKKEEILKT | TCFICGLERD | KFDNKTVSFE | EHIKSEHNMW | HYLYFLVLVK | 
    2650:
    VKDPTEYTGP | ESYVAQMIVE | KNLDWFPRMR | AMSLVSSEGD | SEQNEVRNLQ | 
    2700:
    EKLESTMSLV | KQLSSQLAEL | KEQMTEQRKN | KQRLGFLGSN | TPHVNHHMPP | 
    2701:
    H
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    ELISA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    CLIA Kit for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Polyclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Monoclonal Antibody for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2
    Protein for Bovine Inositol 1,4,5-trisphosphate receptor type 2

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    Precision
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    References
    1. 1.
      "Localization of three types of the inositol 1,4,5-trisphosphate receptor/Ca2+ channel in the secretory granules and coupling with the Ca2+ storage proteins chromogranins A and B."
      Yoo S.H. , Oh Y.S. , Kang M.K. , Huh Y.H. , So S.H. , Park H.S. , Park H.Y.
      J. Biol. Chem.276:45806-45812(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION
      tissue: Adrenal medulla.
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