Itpr2 ELISA Kit for Mouse(Mus musculus) | EIAab.comItpr2 ELISA Kit for Mouse(Mus musculus)

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Itpr2 (Gene name),

Inositol 1,4,5-trisphosphate receptor type 2 (Protein name ), ITPR2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Itpr2(Itpr5);

Protein name:

Inositol 1,4,5-trisphosphate receptor type 2;

Alternative:

Inositol 1,4,5-trisphosphate type V receptor;IP3 receptor isoform 2(IP3R 2;InsP3R2);Type 2 inositol 1,4,5-trisphosphate receptor(Type 2 InsP3 receptor);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotetramer (By similarity). Interacts with CABP1.

Function:

Isoform 3 has neither inositol 1,4,5-trisphosphate binding activity nor calcium releasing activity.

Subcellular Location:

Endoplasmic reticulum membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2701

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3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.393003

KEGG:

mmu:16439

String:

Q9Z329

SMR:

Q9Z329

UniGene:

Mm.7800

Pfam:

PF08709

Uniprot:

Q9Z329

FOR

ELISA Kit for Mouse Inositol 1,4,5-trisphosphate receptor type 2

CLIA Kit for Mouse Inositol 1,4,5-trisphosphate receptor type 2

Polyclonal Antibody for Mouse Inositol 1,4,5-trisphosphate receptor type 2

Monoclonal Antibody for Mouse Inositol 1,4,5-trisphosphate receptor type 2

Protein for Mouse Inositol 1,4,5-trisphosphate receptor type 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant."
Iwai M. , Tateishi Y. , Hattori M. , Mizutani A. , Nakamura T. , Futatsugi A. , Inoue T. , Furuichi T. , Michikawa T. , Mikoshiba K.
J. Biol. Chem.280:10305-10317(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-507 AND ARG-510
strain: C57BL/6J.
tissue: Lung.
2.

"Muscle-specific mRNA isoform encodes a protein composed mainly of the N-terminal 175 residues of type 2 Ins(1,4,5)P3 receptor."
Futatsugi A. , Kuwajima G. , Mikoshiba K.
Biochem. J.334:559-563(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Heart.
3.

"Regulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinase."
Tovey S.C. , Dedos S.G. , Rahman T. , Taylor E.J. , Pantazaka E. , Taylor C.W.
J. Biol. Chem.285:12979-12989(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
4.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
5.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1290-2701
strain: Czech II.
tissue: Mammary tumor.
7.

"Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction."
De Smedt H. , Missiaen L. , Parys J.B. , Bootman M.D. , Mertens L. , Van Den Bosch L. , Casteels R.
J. Biol. Chem.269:21691-21698(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1693-2701 (ISOFORM 1)
strain: C3H.
tissue: Embryo.
8.

"Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin."
De Smedt H. , Missiaen L. , Parys J.B. , Henning R.H. , Sienaert I. , Vanlingen S. , Gijsens A. , Himpens B. , Casteels R.
Biochem. J.322:575-583(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2238-2646 (ISOFORM 1)
strain: C3H.
tissue: Embryo.
9.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-937;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
10.

"Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937."
Betzenhauser M.J. , Fike J.L. , Wagner L.E. II , Yule D.I.
J. Biol. Chem.284:25116-25125(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-937;FUNCTION;MUTAGENESIS OF SER-937; SER-990; SER-1190; SER-1351; SER-1581 AND SER-2633

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