Itpr3 ELISA Kit for Mouse(Mus musculus) | EIAab.comItpr3 ELISA Kit for Mouse(Mus musculus)

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Itpr3 (Gene name),

Inositol 1,4,5-trisphosphate receptor type 3 (Protein name ), ITPR3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Itpr3;

Protein name:

Inositol 1,4,5-trisphosphate receptor type 3;

Alternative:

Type 3 inositol 1,4,5-trisphosphate receptor(Type 3 InsP3 receptor);IP3 receptor isoform 3(IP3R 3;InsP3R3);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotetramer. Interacts with TRPC1, TRPC3, TRPC4 and CABP1 (By similarity). Interacts with SIGMAR1, AKT1 and PML.

Function:

Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.

Subcellular Location:

Endoplasmic reticulum membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2670

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2670:

EQRKRRQRLG | FVDVQNCMSR |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P70227

KEGG:

mmu:16440

UniGene:

Mm.458106

String:

P70227

Pfam:

PF08709

Uniprot:

P70227

FOR

ELISA Kit for Mouse Inositol 1,4,5-trisphosphate receptor type 3

CLIA Kit for Mouse Inositol 1,4,5-trisphosphate receptor type 3

Polyclonal Antibody for Mouse Inositol 1,4,5-trisphosphate receptor type 3

Monoclonal Antibody for Mouse Inositol 1,4,5-trisphosphate receptor type 3

Protein for Mouse Inositol 1,4,5-trisphosphate receptor type 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant."
Iwai M. , Tateishi Y. , Hattori M. , Mizutani A. , Nakamura T. , Futatsugi A. , Inoue T. , Furuichi T. , Michikawa T. , Mikoshiba K.
J. Biol. Chem.280:10305-10317(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-507 AND ARG-510
strain: C57BL/6J.
tissue: Lung.
2.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1857-2670
strain: C57BL/6J.
tissue: Skin.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2181-2670
strain: FVB/N.
tissue: Mammary tumor.
4.

"Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues."
Ross C.A. , Danoff S.K. , Schell M.J. , Snyder S.H. , Ullrich A.
Proc. Natl. Acad. Sci. U.S.A.89:4265-4269(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2406-2609
tissue: Placenta.
5.

"Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin."
De Smedt H. , Missiaen L. , Parys J.B. , Henning R.H. , Sienaert I. , Vanlingen S. , Gijsens A. , Himpens B. , Casteels R.
Biochem. J.322:575-583(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2433-2629
strain: C3H.
tissue: Embryo.
6.

"Regulating ankyrin dynamics: roles of sigma-1 receptors."
Hayashi T. , Su T.-P.
Proc. Natl. Acad. Sci. U.S.A.98:491-496(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SIGMAR1
7.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-916;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
8.

"Lrmp/Jaw1 is expressed in sweet, bitter, and umami receptor-expressing cells."
Shindo Y. , Kim M.R. , Miura H. , Yuuki T. , Kanda T. , Hino A. , Kusakabe Y.
Chem. Senses35:171-177(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LRMP
9.

"Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening."
Yamazaki H. , Chan J. , Ikura M. , Michikawa T. , Mikoshiba K.
J. Biol. Chem.285:36081-36091(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF TRP-168
10.

"PML regulates apoptosis at endoplasmic reticulum by modulating calcium release."
Giorgi C. , Ito K. , Lin H.K. , Santangelo C. , Wieckowski M.R. , Lebiedzinska M. , Bononi A. , Bonora M. , Duszynski J. , Bernardi R. , Rizzuto R. , Tacchetti C. , Pinton P. , Pandolfi P.P.
Science330:1247-1251(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PML AND AKT1;PHOSPHORYLATION;SUBCELLULAR LOCATION
11.

"Tespa1 is a novel inositol 1,4,5-trisphosphate receptor binding protein in T and B lymphocytes."
Matsuzaki H. , Fujimoto T. , Ota T. , Ogawa M. , Tsunoda T. , Doi K. , Hamabashiri M. , Tanaka M. , Shirasawa S.
FEBS Open Bio2:255-259(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TESPA1
12.

"Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating."
Chan J. , Yamazaki H. , Ishiyama N. , Seo M.D. , Mal T.K. , Michikawa T. , Mikoshiba K. , Ikura M.
J. Biol. Chem.285:36092-36099(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 1-224

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