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Index > Protein center > KRT20(Gene name) > Human
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  • KRT20 (Gene name),
  • Keratin, type I cytoskeletal 20 (Protein name ),  K1C20_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    KRT20;
    Protein name:
    Keratin, type I cytoskeletal 20;
    Alternative:
    Keratin-20(K20);Cytokeratin-20(CK-20);Protein IT;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterotetramer of two type I and two type II keratins. Associates with KRT8.
    Function:
    Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    424
    Sequence:
    50:
    MDFSRRSFHR | SLSSSLQAPV | VSTVGMQRLG | TTPSVYGGAG | GRGIRISNSR | 
    100:
    HTVNYGSDLT | GGGDLFVGNE | KMAMQNLNDR | LASYLEKVRT | LEQSNSKLEV | 
    150:
    QIKQWYETNA | PRAGRDYSAY | YRQIEELRSQ | IKDAQLQNAR | CVLQIDNAKL | 
    200:
    AAEDFRLKYE | TERGIRLTVE | ADLQGLNKVF | DDLTLHKTDL | EIQIEELNKD | 
    250:
    LALLKKEHQE | EVDGLHKHLG | NTVNVEVDAA | PGLNLGVIMN | EMRQKYEVMA | 
    300:
    QKNLQEAKEQ | FERQTAVLQQ | QVTVNTEELK | GTEVQLTELR | RTSQSLEIEL | 
    350:
    QSHLSMKESL | EHTLEETKAR | YSSQLANLQS | LLSSLEAQLM | QIRSNMERQN | 
    400:
    NEYHILLDIK | TRLEQEIATY | RRLLEGEDVK | TTEYQLSTLE | ERDIKKTRKI | 
    424:
    KTVVQEVVDG | KVVSSEVKEV | EENI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    Pfam:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Keratin, type I cytoskeletal 20
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    E1240h
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    ELISA Kit for Human Keratin, type I cytoskeletal 20
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    ELISA Kit for Human Keratin, type I cytoskeletal 20
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    ELISA Kit for Human Keratin, type I cytoskeletal 20
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    E1240b
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    ELISA Kit for Human Keratin, type I cytoskeletal 20
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    E1240m
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    CLIA Kit for Human Keratin, type I cytoskeletal 20
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    U1240b
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    96T
    CLIA Kit for Human Keratin, type I cytoskeletal 20
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    CLIA Kit for Human Keratin, type I cytoskeletal 20
    Cat.:
    U1240h
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    MSDS:
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    96T
    Range:
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    CLIA Kit for Human Keratin, type I cytoskeletal 20
    Cat.:
    U1240r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Keratin, type I cytoskeletal 20
    Cat.:
    U1240m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Keratin, type I cytoskeletal 20
    Cat.:
    P1240Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Keratin, type I cytoskeletal 20
    Polyclonal Antibody for Human Keratin, type I cytoskeletal 20
    Polyclonal Antibody for Human Keratin, type I cytoskeletal 20
    Cat.:
    P1240Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Keratin, type I cytoskeletal 20
    Cat.:
    P1240Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Keratin, type I cytoskeletal 20
    Monoclonal Antibody for Human Keratin, type I cytoskeletal 20
    Monoclonal Antibody for Human Keratin, type I cytoskeletal 20
    Monoclonal Antibody for Human Keratin, type I cytoskeletal 20
    Monoclonal Antibody for Human Keratin, type I cytoskeletal 20
    Protein for Human Keratin, type I cytoskeletal 20
    Protein for Human Keratin, type I cytoskeletal 20
    Protein for Human Keratin, type I cytoskeletal 20
    Protein for Human Keratin, type I cytoskeletal 20
    Protein for Human Keratin, type I cytoskeletal 20

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    References
    1. 1.
      "The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas."
      Moll R. , Zimbelmann R. , Goldschmidt M.D. , Keith M. , Laufer J. , Kasper M. , Koch P.J. , Franke W.W.
      Differentiation53:75-93(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];DEVELOPMENTAL STAGE
      tissue: Intestine.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASN-129
      tissue: Small intestine.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell marker."
      Zhou Q. , Cadrin M. , Herrmann H. , Chen C.-H. , Chalkley R.J. , Burlingame A.L. , Omary M.B.
      J. Biol. Chem.281:16453-16461(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 11-28;FUNCTION;INTERACTION WITH KRT8;PHOSPHORYLATION AT SER-13;CLEAVAGE AT ASP-228;MUTAGENESIS OF SER-13 AND SER-14
    5. 5.
      "Differential localization by in situ hybridization of distinct keratin mRNA species during intestinal epithelial cell development and differentiation."
      Calnek D. , Quaroni A.
      Differentiation53:95-104(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 86-424
      tissue: Intestine.
    6. 6.
      "Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns."
      Moll R. , Schiller D.L. , Franke W.W.
      J. Cell Biol.111:567-580(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    7. 7.
      "An immunohistological study of cytokeratin 20 in human and mammalian oral epithelium."
      Barrett A.W. , Cort E.M. , Patel P. , Berkovitz B.K.B.
      Arch. Oral Biol.45:879-887(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KRT8;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    8. 8.
      "Keratin 20 helps maintain intermediate filament organization in intestinal epithelia."
      Zhou Q. , Toivola D.M. , Feng N. , Greenberg H.B. , Franke W.W. , Omary M.B.
      Mol. Biol. Cell14:2959-2971(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF ARG-80
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ARG-4
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CYS-214
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