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Index > Protein center > Krt1(Gene name) > Mouse
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  • Krt1 (Gene name),
  • Keratin, type II cytoskeletal 1 (Protein name ),  K2C1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Krt1(Krt2-1);
    Protein name:
    Keratin, type II cytoskeletal 1;
    Alternative:
    Cytokeratin-1(CK-1);67 kDa cytokeratin;Type-II keratin Kb1;Keratin-1(K1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterotetramer of two type I and two type II keratins. Keratin-1 is generally associated with keratin-10. Interacts with ITB1 in the presence of GNB2L1 and SRC, and with GNB2L1.
    Function:
    May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein kinase C (RACK1/GNB2L1).
    Subcellular Location:
    Cell membrane
    Protein Attributes:
    Sequence length:
    637
    Sequence:
    50:
    MSLQCSSRSL | CRGGGGSRNF | SSGSAGLVSF | QRRSTSSSMR | RSGGGGGGRF | 
    100:
    SGGGFCGSSG | SGFGSKSLMN | LGGGRSISKS | VAGGGGSFCG | GFGGGSYGGG | 
    150:
    GFGGGSYGGG | GFGGGSFGGG | GFGGSGFGGG | LGGGGGFGSG | GGFGGGRFGS | 
    200:
    MGPVCPPGGI | QEVTINQSLL | QPLNVEVDPQ | IQKVKSQERE | QIKSLNDKFA | 
    250:
    SFIDKVRFLE | QQNQVLQTKW | ELLQQVDTTT | RTQNLDPFFE | NYISILRRKV | 
    300:
    DSLKSDQSRM | DSELKNMQDL | VEEYRTKYED | EINKRTNAEN | EFVTIKKDVD | 
    350:
    SAYMTKVELQ | AKADALQQDI | DFFSALYQME | MSQMQTQISE | TNVVLSMDNN | 
    400:
    RSLDLDGIIS | EVKAQYDSIC | QRSKAEAETF | YQSKYEELQI | TAGKHGDSVR | 
    450:
    NTKMEISELN | RMIQRLRSEI | DGCKKQISQI | QQNINDAEQR | GEKALKDAQN | 
    500:
    KLNEIEDALS | QCKEDLARLL | RDFQELMNTK | LALDMEIATY | KKLLEGEEIR | 
    550:
    MSGECTPNVS | VSVSTSHTSM | SGSSSRGGGS | GGGRYGGGGS | YGGGSGGGSY | 
    600:
    GGSSGGGGSG | GSYGGGSGGG | SYGGGSGGGS | SGSHRGGSGG | GGGSSGGSYG | 
    637:
    GSSGGGRGGS | SSGGGGVKSS | GSSTVKFVST | SYSRGTK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    E2282h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    E2282r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    E2282m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    E2282d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    U2282r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    U2282d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    U2282h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    U2282m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Polyclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    P2282Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    P2282Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Cat.:
    P2282Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Monoclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Monoclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Monoclonal Antibody for Mouse Keratin, type II cytoskeletal 1
    Protein for Mouse Keratin, type II cytoskeletal 1
    Protein for Mouse Keratin, type II cytoskeletal 1
    Protein for Mouse Keratin, type II cytoskeletal 1
    Protein for Mouse Keratin, type II cytoskeletal 1

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    References
    1. 1.
      "Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits."
      Steinert P.M. , Parry D.A.D. , Idler W.W. , Johnson L.D. , Steven A.C. , Roop D.R.
      J. Biol. Chem.260:7142-7149(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Roop D.R.
      Submitted (1999-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Head.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 199-205; 208-219 AND 286-296;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    6. 6.
      "Sequential reorganization of cornified cell keratin filaments involving filaggrin-mediated compaction and keratin 1 deimination."
      Ishida-Yamamoto A. , Senshu T. , Eady R.A.J. , Takahashi H. , Shimizu H. , Akiyama M. , Iizuka H.
      J. Invest. Dermatol.118:282-287(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CITRULLINATION
    7. 7.
      "A mouse keratin 1 mutation causes dark skin and epidermolytic hyperkeratosis."
      McGowan K.A. , Aradhya S. , Fuchs H. , de Angelis M.H. , Barsh G.S.
      J. Invest. Dermatol.126:1013-1016(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT EHK PRO-194
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