Prkacb ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPrkacb ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Prkacb(Gene name) > Rat

Prkacb (Gene name),

cAMP-dependent protein kinase catalytic subunit beta (Protein name ), KAPCB_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Prkacb(Pkacb);

Protein name:

cAMP-dependent protein kinase catalytic subunit beta(PKA C-beta);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. The cAMP-dependent protein kinase catalytic subunit binds PJA2.

Function:

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Subcellular Location:

Cytoplasm Cell membrane Nucleus Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm.

Protein Attributes:

Sequence length:

351

Sequence:

50:

100:

150:

200:

250:

300:

350:

351:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000043572

UniGene:

Rn.202491

KEGG:

rno:293508

SMR:

P68182

Pfam:

PF00069

String:

P68182

Uniprot:

P68182

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ELISA Kit for Rat PKA C-beta

Cat.:

E1987h

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Packing:

96T

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ELISA Kit for Rat PKA C-beta

Cat.:

E1987m

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96T

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ELISA Kit for Rat PKA C-beta

Cat.:

E1987r

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96T

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ELISA Kit for Rat PKA C-beta

Cat.:

E1987b

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96T

ELISA Kit for Rat PKA C-beta

Cat.:

E1987p

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Packing:

96T

CLIA Kit for Rat PKA C-beta

Cat.:

U1987b

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MSDS:

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Packing:

96T

CLIA Kit for Rat PKA C-beta

Cat.:

U1987h

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat PKA C-beta

Cat.:

U1987p

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MSDS:

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Packing:

96T

CLIA Kit for Rat PKA C-beta

Cat.:

U1987m

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MSDS:

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Packing:

96T

CLIA Kit for Rat PKA C-beta

Cat.:

U1987r

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Packing:

96T

Polyclonal Antibody for Rat PKA C-beta

Cat.:

P1987Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat PKA C-beta

Cat.:

P1987Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat PKA C-beta

Cat.:

P1987Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat PKA C-beta

Monoclonal Antibody for Rat PKA C-beta

Protein for Rat PKA C-beta

Cat.:

R1987h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Rat PKA C-beta

Cat.:

R1987m

Price:

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Packing:

1mg

Purity:

>90%

Protein for Rat PKA C-beta

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular structure of the C beta catalytic subunit of rat cAMP-dependent protein kinase and differential expression of C alpha and C beta isoforms in rat tissues and cultured cells."
Shuntoh H. , Sakamoto N. , Matsuyama S. , Saitoh M. , Tanaka C.
Biochim. Biophys. Acta1131:175-180(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"A conserved deamidation site at Asn 2 in the catalytic subunit of mammalian cAMP-dependent protein kinase detected by capillary LC-MS and tandem mass spectrometry."
Jedrzejewski P.T. , Girod A. , Tholey A. , Koenig N. , Thullner S. , Kinzel V. , Bossemeyer D.
Protein Sci.7:457-469(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-8;DEAMIDATION AT ASN-3

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