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Index > Protein center > Ccbl1(Gene name) > Rat
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  • Ccbl1 (Gene name),
  • Kynurenine--oxoglutarate transaminase 1, mitochondrial (Protein name ),  KAT1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ccbl1(Kat);
    Protein name:
    Kynurenine--oxoglutarate transaminase 1, mitochondrial(Kynurenine--oxoglutarate transaminase I);
    Alternative:
    Glutamine transaminase K(GTK);4.4.1.13;Cysteine-S-conjugate beta-lyase);Kynurenine aminotransferase I(KATI);2.6.1.64;Glutamine--phenylpyruvate transaminase);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
    Subcellular Location:
    Isoform 1 Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    457
    Sequence:
    50:
    MFRSAAALSV | HLMWPLWGRK | AGASLTRCLH | QSLTMTKRLQ | ARRLDGIDQN | 
    100:
    LWVEFGKLTK | EYDVVNLGQG | FPDFSPPDFA | TQAFQQATSG | NFMLNQYTRA | 
    150:
    FGYPPLTNVL | ASFFGKLLGQ | EMDPLTNVLV | TVGAYGALFT | RFQALVDEGD | 
    200:
    EVIIMEPAFD | CYEPMTMMAG | GCPVFVTLKP | SPAPKGKLGA | SNDWQLDPAE | 
    250:
    LASKFTPRTK | ILVLNTPNNP | LGKVFSRMEL | ELVANLCQQH | DVVCISDEVY | 
    300:
    QWLVYDGHQH | VSIASLPGMW | DRTLTIGSAG | KSFSATGWKV | GWVMGPDNIM | 
    350:
    KHLRTVHQNS | IFHCPTQAQA | AVAQCFEREQ | QHFGQPSSYF | LQLPQAMELN | 
    400:
    RDHMIRSLQS | VGLKLWISQG | SYFLIADISD | FKSKMPDLPG | AEDEPYDRRF | 
    450:
    AKWMIKNMGL | VGIPVSTFFS | RPHQKDFDHY | IRFCFVKDKA | TLQAMDERLR | 
    457:
    KWKELQP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    E0282h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    E0282r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    E0282m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    U0282r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    U0282h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    U0282m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    P0282Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    P0282Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Kynurenine--oxoglutarate transaminase I
    Cat.:
    P0282Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Kynurenine--oxoglutarate transaminase I
    Monoclonal Antibody for Rat Kynurenine--oxoglutarate transaminase I
    Monoclonal Antibody for Rat Kynurenine--oxoglutarate transaminase I
    Protein for Rat Kynurenine--oxoglutarate transaminase I
    Protein for Rat Kynurenine--oxoglutarate transaminase I
    Protein for Rat Kynurenine--oxoglutarate transaminase I

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and expression of a cDNA coding for rat kidney cytosolic cysteine conjugate beta-lyase."
      Perry S.J. , Schofield M.A. , MacFarlane M. , Lock E.A. , King L.J. , Gibson G.G. , Goldfarb P.S.
      Mol. Pharmacol.43:660-665(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);PROTEIN SEQUENCE OF 39-62; 228-259 AND 388-401;TISSUE SPECIFICITY
      tissue: Kidney.
    2. 2.
      "Molecular cloning of rat kynurenine aminotransferase: identity with glutamine transaminase K."
      Mosca M. , Cozzi L. , Breton J. , Speciale C. , Okuno E. , Schwarcz R. , Benatti L.
      FEBS Lett.353:21-24(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    3. 3.
      "Identification of a mitochondrial form of kynurenine aminotransferase/glutamine transaminase K from rat brain."
      Malherbe P. , Alberati-Giani D. , Koehler C. , Cesura A.M.
      FEBS Lett.367:141-144(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Cerebellum.
    4. 4.
      "Tissue expression and translational control of rat kynurenine aminotransferase/glutamine transaminase K mRNAs."
      Mosca M. , Croci C. , Mostardini M. , Breton J. , Malyszko J. , Avanzi N. , Toma S. , Benatti L. , Gatti S.
      Biochim. Biophys. Acta1628:1-10(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
    5. 5.
      "Crystallization and characterization of human liver kynurenine--glyoxylate aminotransferase. Identity with alanine--glyoxylate aminotransferase and serine--pyruvate aminotransferase."
      Okuno E. , Minatogawa Y. , Nakamura M. , Kamoda N. , Nakanishi J. , Makino M. , Kido R.
      Biochem. J.189:581-590(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;SUBSTRATE SPECIFICITY;SUBUNIT;PH DEPENDENCE
    6. 6.
      "Measurement of rat brain kynurenine aminotransferase at physiological kynurenine concentrations."
      Okuno E. , Schmidt W. , Parks D.A. , Nakamura M. , Schwarcz R.
      J. Neurochem.57:533-540(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY AS KYNURENINE--OXOGLUTARATE TRANSAMINASE;KINETIC PARAMETERS;ENZYME REGULATION
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