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Index > Protein center > CSNK1G2(Gene name) > Human
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  • CSNK1G2 (Gene name),
  • Casein kinase I isoform gamma-2 (Protein name ),  KC1G2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CSNK1G2(CK1G2);
    Protein name:
    Casein kinase I isoform gamma-2(CKI-gamma 2);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    415
    Sequence:
    50:
    MDFDKKGGKG | ETEEGRRMSK | AGGGRSSHGI | RSSGTSSGVL | MVGPNFRVGK | 
    100:
    KIGCGNFGEL | RLGKNLYTNE | YVAIKLEPIK | SRAPQLHLEY | RFYKQLSATE | 
    150:
    GVPQVYYFGP | CGKYNAMVLE | LLGPSLEDLF | DLCDRTFTLK | TVLMIAIQLI | 
    200:
    TRMEYVHTKS | LIYRDVKPEN | FLVGRPGTKR | QHAIHIIDFG | LAKEYIDPET | 
    250:
    KKHIPYREHK | SLTGTARYMS | INTHLGKEQS | RRDDLEALGH | MFMYFLRGSL | 
    300:
    PWQGLKADTL | KERYQKIGDT | KRATPIEVLC | ENFPEEMATY | LRYVRRLDFF | 
    350:
    EKPDYDYLRK | LFTDLFDRSG | FVFDYEYDWA | GKPLPTPIGT | VHTDLPSQPQ | 
    400:
    LRDKTQPHSK | NQALNSTNGE | LNADDPTAGH | SNAPITAPAE | VEVADETKCC | 
    415:
    CFFKRRKRKS | LQRHK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    String:
    MIM:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human CKI-gamma 2
    ELISA Kit for Human CKI-gamma 2
    ELISA Kit for Human CKI-gamma 2
    CLIA Kit for Human CKI-gamma 2
    CLIA Kit for Human CKI-gamma 2
    CLIA Kit for Human CKI-gamma 2
    Polyclonal Antibody for Human CKI-gamma 2
    Polyclonal Antibody for Human CKI-gamma 2
    Polyclonal Antibody for Human CKI-gamma 2
    Monoclonal Antibody for Human CKI-gamma 2
    Monoclonal Antibody for Human CKI-gamma 2
    Monoclonal Antibody for Human CKI-gamma 2
    Protein for Human CKI-gamma 2
    Protein for Human CKI-gamma 2
    Protein for Human CKI-gamma 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and chromosomal mapping of human casein kinase I gamma 2 (CSNK1G2)."
      Kitabayashi A.N. , Kusuda J. , Hirai M. , Hashimoto K.
      Genomics46:133-137(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Testis.
    2. 2.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
      Goshima N. , Kawamura Y. , Fukumoto A. , Miura A. , Honma R. , Satoh R. , Wakamatsu A. , Yamamoto J. , Kimura K. , Nishikawa T. , Andoh T. , Iida Y. , Ishikawa K. , Ito E. , Kagawa N. , Kaminaga C. , Kanehori K. , Kawakami B. , more...
      Nat. Methods5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Colon.
      tissue: Muscle.
    7. 7.
      "Polymorphisms of casein kinase I gamma 2 gene associated with simple febrile seizures in Chinese Han population."
      Yinan M. , Yu Q. , Zhiyue C. , Jianjun L. , Lie H. , Liping Z. , Jianhui Z. , Fang S. , Dingfang B. , Qing L. , Xiru W.
      Neurosci. Lett.368:2-6(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN BRAIN DEVELOPMENT
    8. 8.
      "Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase."
      Mishra S.K. , Yang Z. , Mazumdar A. , Talukder A.H. , Larose L. , Kumar R.
      Oncogene23:4422-4429(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS MTA1 KINASE;INTERACTION WITH MTA1;SUBCELLULAR LOCATION;ENZYME REGULATION
    9. 9.
      "SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein."
      Shirogane T. , Jin J. , Ang X.L. , Harper J.W.
      J. Biol. Chem.280:26863-26872(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PER1 STABILITY
    10. 10.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling."
      Guo X. , Waddell D.S. , Wang W. , Wang Z. , Liberati N.T. , Yong S. , Liu X. , Wang X.-F.
      Oncogene27:7235-7247(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS SMAD3 KINASE;INTERACTION WITH SMAD3
    12. 12.
      "Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin."
      Tomishige N. , Kumagai K. , Kusuda J. , Nishijima M. , Hanada K.
      Mol. Biol. Cell20:348-357(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS COL4A3BP/CERT KINASE
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    15. 15.
      "The structure of casein kinase 1 gamma 2."
      Bunkoczi G. , Rellos P. , Das S. , Ugochukwu E. , Fedorov O. , Sobott F. , Eswaran J. , Amos A. , Ball L. , Von Delft F. , Bullock A. , Debreczeni J. , Turnbull A. , Sundstrom M. , Weigelt J. , Arrowsmith C. , Edwards A. , Knapp S.
      Submitted (2011-07) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 43-353 IN COMPLEX WITH 5-IODOTUBERCIDIN
    16. 16.
      "Patterns of somatic mutation in human cancer genomes."
      Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
      Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] LEU-189; GLY-194; THR-196; CYS-206; HIS-206; SER-207; GLN-208; CYS-217 AND MET-223
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