KCNN1 ELISA Kit for Human(Homo sapiens) | EIAab.comKCNN1 ELISA Kit for Human(Homo sapiens)

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KCNN1 (Gene name),

Small conductance calcium-activated potassium channel protein 1 (Protein name ), KCNN1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

KCNN1(SK);

Protein name:

Small conductance calcium-activated potassium channel protein 1(SK1;SKCa 1;SKCa1);

Alternative:

KCa2.1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.

Function:

Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

543

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

543:

GLIAQAIRPP | PPPLPPRPGP | GPQDQAARSS | PCRWTPVAPS | DCG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q92952

STRING:

9606.ENSP00000222249

KEGG:

hsa:3780

Pfam:

PF02888

String:

Q92952

UniGene:

Hs.158173

MIM:

602982

Uniprot:

Q92952

FOR

ELISA Kit for Human SK1

CLIA Kit for Human SK1

Polyclonal Antibody for Human SK1

Monoclonal Antibody for Human SK1

Protein for Human SK1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Small-conductance, calcium-activated potassium channels from mammalian brain."
Koehler M. , Hirschberg B. , Bond C.T. , Kinzie J.M. , Marrion N.V. , Maylie J. , Adelman J.P.
Science273:1709-1714(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Hippocampus.
2.

"Gene structure and chromosome mapping of the human small-conductance calcium-activated potassium channel SK1 gene (KCNN1)."
Litt M. , LaMorticella D. , Bond C.T. , Adelman J.P.
Cytogenet. Cell Genet.86:70-73(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Molecular cloning of a small-conductance calcium-activated potassium channel from human fetal brain."
Tagaya M. , Higashioka M. , Takagaki K. , Ohgi T.
Submitted (2005-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Fetal brain.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Fetal brain.

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