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Index > Protein center > Kcnn1(Gene name) > Rat
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  • Kcnn1 (Gene name),
  • Small conductance calcium-activated potassium channel protein 1 (Protein name ),  KCNN1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Kcnn1(Sk1);
    Protein name:
    Small conductance calcium-activated potassium channel protein 1(SK1;SKCa 1;SKCa1);
    Alternative:
    KCa2.1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.
    Function:
    Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    536
    Sequence:
    50:
    MSSRSHNGSV | GRPLGSGPGF | LGWEPVDPEA | GRPRQPTQGP | GLQMMAKGQP | 
    100:
    AGLSPSGPRG | HSQAQEEEEE | EEDEDRPGSG | KPPTVSHRLG | HRRALFEKRK | 
    150:
    RLSDYALIFG | MFGIVVMVTE | TELSWGVYTK | ESLCSFALKC | LISLSTVILL | 
    200:
    GLVILYHARE | IQLFLVDNGA | DDWRIAMTWE | RVSLISLELA | VCAIHPVPGH | 
    250:
    YRFTWTARLA | FSLVPSAAEA | DVDVLLSIPM | FLRLYLLARV | MLLHSRIFTD | 
    300:
    ASSRSIGALN | RVTFNTRFVT | KTLMTICPGT | VLLVFSISSW | IVAAWTVRVC | 
    350:
    ERYHDKQEVT | SNFLGAMWLI | SITFLSIGYG | DMVPHTYCGK | GVCLLTGIMG | 
    400:
    AGCTALVVAV | VARKLELTKA | EKHVHNFMMD | TQLTKRVKNA | AANVLRETWL | 
    450:
    IYKHTRLVKK | PDQSRVRKHQ | RKFLQAIHQA | QKLRTVKIEQ | GKVNDQANTL | 
    500:
    ADLAKAQSIA | YEVVSELQAQ | QEELEARLAA | LESRLDVLGA | SLQALPSLIA | 
    536:
    QAICPLPPPW | PGPSHLTTAA | QSPQSHWLPT | TASDCG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat SK1
    ELISA Kit for Rat SK1
    ELISA Kit for Rat SK1
    CLIA Kit for Rat SK1
    CLIA Kit for Rat SK1
    CLIA Kit for Rat SK1
    Polyclonal Antibody for Rat SK1
    Polyclonal Antibody for Rat SK1
    Polyclonal Antibody for Rat SK1
    Monoclonal Antibody for Rat SK1
    Monoclonal Antibody for Rat SK1
    Monoclonal Antibody for Rat SK1
    Protein for Rat SK1
    Protein for Rat SK1
    Protein for Rat SK1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "hSK4, a member of a novel subfamily of calcium-activated potassium channels."
      Joiner W.J. , Wang L.-Y. , Tang M.D. , Kaczmarek L.K.
      Proc. Natl. Acad. Sci. U.S.A.94:11013-11018(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "Small-conductance, calcium-activated potassium channels from mammalian brain."
      Koehler M. , Hirschberg B. , Bond C.T. , Kinzie J.M. , Marrion N.V. , Maylie J. , Adelman J.P.
      Science273:1709-1714(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 79-536
      strain: Sprague-Dawley.
      tissue: Brain.
    3. 3.
      "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
      Hoffert J.D. , Pisitkun T. , Wang G. , Shen R.-F. , Knepper M.A.
      Proc. Natl. Acad. Sci. U.S.A.103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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