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Index > Protein center > CKB(Gene name) > Human
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  • CKB (Gene name),
  • Creatine kinase B-type (Protein name ),  KCRB_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CKB(CKBB);
    Protein name:
    Creatine kinase B-type;
    Alternative:
    Creatine kinase B chain;B-CK;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
    Function:
    Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    381
    Sequence:
    50:
    MPFSNSHNAL | KLRFPAEDEF | PDLSAHNNHM | AKVLTPELYA | ELRAKSTPSG | 
    100:
    FTLDDVIQTG | VDNPGHPYIM | TVGCVAGDEE | SYEVFKDLFD | PIIEDRHGGY | 
    150:
    KPSDEHKTDL | NPDNLQGGDD | LDPNYVLSSR | VRTGRSIRGF | CLPPHCSRGE | 
    200:
    RRAIEKLAVE | ALSSLDGDLA | GRYYALKSMT | EAEQQQLIDD | HFLFDKPVSP | 
    250:
    LLLASGMARD | WPDARGIWHN | DNKTFLVWVN | EEDHLRVISM | QKGGNMKEVF | 
    300:
    TRFCTGLTQI | ETLFKSKDYE | FMWNPHLGYI | LTCPSNLGTG | LRAGVHIKLP | 
    350:
    NLGKHEKFSE | VLKRLRLQKR | GTGGVDTAAV | GGVFDVSNAD | RLGFSEVELV | 
    381:
    QMVVDGVKLL | IEMEQRLEQG | QAIDDLMPAQ | K
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    KEGG:
    SMR:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Creatine kinase B-type
    Cat.:
    E2030h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Creatine kinase B-type
    Cat.:
    E2030p
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    Packing:
    96T
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    ELISA Kit for Human Creatine kinase B-type
    Cat.:
    E2030b
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    MSDS:
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    96T
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    ELISA Kit for Human Creatine kinase B-type
    Cat.:
    E2030m
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    MSDS:
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    96T
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    ELISA Kit for Human Creatine kinase B-type
    MSDS:
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    ELISA Kit for Human Creatine kinase B-type
    Cat.:
    E2030c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Creatine kinase B-type
    Cat.:
    E2030r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Creatine kinase B-type
    Cat.:
    E2030d
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase B-type
    Cat.:
    U2030d
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase B-type
    Cat.:
    U2030r
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase B-type
    Cat.:
    U2030m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Creatine kinase B-type
    Cat.:
    U2030b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Creatine kinase B-type
    MSDS:
    Please sign in first.
    CLIA Kit for Human Creatine kinase B-type
    Cat.:
    U2030h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Creatine kinase B-type
    MSDS:
    Please sign in first.
    CLIA Kit for Human Creatine kinase B-type
    Cat.:
    U2030c
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Creatine kinase B-type
    Cat.:
    P2030Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Creatine kinase B-type
    Polyclonal Antibody for Human Creatine kinase B-type
    Polyclonal Antibody for Human Creatine kinase B-type
    Polyclonal Antibody for Human Creatine kinase B-type
    Cat.:
    P2030Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Creatine kinase B-type
    Polyclonal Antibody for Human Creatine kinase B-type
    Cat.:
    P2030Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Monoclonal Antibody for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type
    Protein for Human Creatine kinase B-type

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number."
      Villarreal-Levy G. , Ma T.S. , Kerner S.A. , Roberts R. , Perryman M.B.
      Biochem. Biophys. Res. Commun.144:1116-1127(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structure and expression of the human creatine kinase B gene."
      Mariman E.C.M. , Broers C.A.M. , Claesen C.A.A. , Tesser G.I. , Wieringa B.
      Genomics1:126-137(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Human creatine kinase-B complementary DNA. Nucleotide sequence, gene expression in lung cancer, and chromosomal assignment to two distinct loci."
      Kaye F.J. , McBride O.W. , Battey J.F. , Gazder A.F. , Sausville E.A.
      J. Clin. Invest.79:1412-1420(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Complete nucleotide sequence of the human creatine kinase B gene."
      Mariman E.C.M. , Schepens J.T.G. , Wieringa B.
      Nucleic Acids Res.17:6385-6385(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Brain.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Cerebellum.
      tissue: Subthalamic nucleus.
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      NIEHS SNPs program
      Submitted (2005-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-177 AND LEU-309
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Eye.
      tissue: Lung.
    10. 10.
      "Isolation of a functional human gene for brain creatine kinase."
      Daouk G.H. , Kaddurah-Daouk R. , Putney S. , Kingston R. , Schimmel P.
      J. Biol. Chem.263:2442-2446(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-97
    11. 11.
      "Protein analysis of human maculae in relation to age-related maculopathy."
      Kliffen M. , de Jong P.T.V.M. , Luider T.M.
      Lab. Invest.73:267-272(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-22
      tissue: Eye.
    12. 12.
      Bienvenut W.V. , Heiserich L. , Gottlieb E.
      Submitted (2008-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-11; 33-43; 157-172; 224-236; 253-265; 308-314 AND 342-366;CLEAVAGE OF INITIATOR METHIONINE;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Colon carcinoma.
    13. 13.
      Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 33-43; 87-96; 108-130; 157-172; 224-236; 253-265; 320-341 AND 359-381;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    14. 14.
      "Determination of the catalytic site of creatine kinase by site-directed mutagenesis."
      Lin L. , Perryman M.B. , Friedman D. , Roberts R. , Ma T.S.
      Biochim. Biophys. Acta1206:97-104(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF CYS-283; ARG-292 AND ASP-340
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-35 AND SER-199;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    16. 16.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "Structural studies of human brain-type creatine kinase complexed with the ADP-Mg2+-NO3- -creatine transition-state analogue complex."
      Bong S.M. , Moon J.H. , Nam K.H. , Lee K.S. , Chi Y.M. , Hwang K.Y.
      FEBS Lett.582:3959-3965(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH ADP AND CREATINE;ATP-BINDING SITES;SUBSTRATE-BINDING SITES
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