Khdrbs2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comKhdrbs2 ELISA Kit for Rat(Rattus norvegicus)

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Khdrbs2 (Gene name),

KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Protein name ), KHDR2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Khdrbs2(Slm1);

Protein name:

KH domain-containing, RNA-binding, signal transduction-associated protein 2;

Alternative:

Sam68-like mammalian protein 1(SLM-1;rSLM-1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Self-associates to form homooligomers. Interacts with SAFB, SFRS9 and YTHDC1. Found in a complex with KHDRBS1, KHDRBS2 and KHDRBS3. Interacts with RBMX (By similarity). Interacts with the SH3 domains of FYN and PLCG1 (By similarity). Interacts with the SH2 domains of FYN, GRAP2, PLCG1 and RASA1 (By similarity). Interacts with RBMX.

Function:

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis (By similarity). Binds both poly(A) and poly(U) homopolymers (By similarity). Phosphorylation by PTK6 inhibits its RNA-binding ability.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

349

Sequence:

50:

100:

150:

200:

250:

300:

349:

EYYDYGHGVN | EDAYDSYAPE | EWTTTRSSLK | APPPRSARGG | YREHPYGRY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:170843

String:

Q920F3

UniGene:

Rn.154423

STRING:

10116.ENSRNOP00000016579

Pfam:

PF00013

Uniprot:

Q920F3

FOR

ELISA Kit for Rat KH domain-containing, RNA-binding, signal transduction-associated protein 2

CLIA Kit for Rat KH domain-containing, RNA-binding, signal transduction-associated protein 2

Polyclonal Antibody for Rat KH domain-containing, RNA-binding, signal transduction-associated protein 2

Monoclonal Antibody for Rat KH domain-containing, RNA-binding, signal transduction-associated protein 2

Protein for Rat KH domain-containing, RNA-binding, signal transduction-associated protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1."
Stoss O. , Novoyatleva T. , Gencheva M. , Olbrich M. , Benderska N. , Stamm S.
Mol. Cell. Neurosci.27:8-21(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBUNIT;INTERACTION WITH RBMX; SAFB; SFRS9 AND YTHDC1;PHOSPHORYLATION;TISSUE SPECIFICITY
tissue: Brain.
2.

"Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA."
Heinrich B. , Zhang Z. , Raitskin O. , Hiller M. , Benderska N. , Hartmann A.M. , Bracco L. , Elliott D. , Ben-Ari S. , Soreq H. , Sperling J. , Sperling R. , Stamm S.
J. Biol. Chem.284:14303-14315(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RBMX

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