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Index > Protein center > Kif2c(Gene name) > Mouse
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  • Kif2c (Gene name),
  • Kinesin-like protein KIF2C (Protein name ),  KIF2C_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Kif2c;
    Protein name:
    Kinesin-like protein KIF2C;
    Alternative:
    Mitotic centromere-associated kinesin(MCAK);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with CENPH. Interacts with MTUS2/TIP150; the interaction is direct. Interacts with MAPRE1; the interaction is direct, regulated by phosphorylation and is probably required for targeting to growing microtubule plus ends.
    Function:
    Promotes ATP-dependent removal of tubulin dimers from microtubules. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.
    Subcellular Location:
    Cytoplasm cytoskeleton Nucleus Chromosome centromere Chromosome centromere kinetochore Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1. Centromeric localization requires the presence of BUB1 and SGOL2.
    Protein Attributes:
    Sequence length:
    721
    Sequence:
    50:
    MESLHARLFP | GLSINIQRSN | GLIHPANIST | VNVEKSCVSV | EWIEGGTTKG | 
    100:
    KEIDIDDVAA | INPELLQLLP | LRPKDSLPLQ | ENVTVPKQKR | KSVNSKIPAL | 
    150:
    KEGLRSRSTR | MSTVSEVRIP | AQENEMEVEL | PVPTNSRKQF | AIPSHPRASC | 
    200:
    STVTELPLLM | VSEEAEEQAH | STRSTSSANP | GNSVRRKSCI | VKEMEKMKNK | 
    250:
    REEKRAQNSE | LRIKRAQEYD | SSFPNWEFAR | MIKEFRVTME | CSPLTVTDPI | 
    300:
    EEHRICVCVR | KRPLNKQELA | KKEIDVISVP | SKCLLLVHEP | KLKVDLTKYL | 
    350:
    ENQAFCFDFA | FDETASNEVV | YRFTARPLVQ | TIFEGGKATC | FAYGQTGSGK | 
    400:
    THTMGGDLSG | KSQNASKGIY | AMASRDVFLL | KNQPRYRNLN | LEVYVTFFEI | 
    450:
    YNGKVFDLLN | KKAKLRVLED | SRQQVQVVGL | QEYLVTCADD | VIKMINMGSA | 
    500:
    CRTSGQTFAN | SNSSRSHACF | QILLRTKGRL | HGKFSLVDLA | GNERGADTSS | 
    550:
    ADRQTRMEGA | EINKSLLALK | ECIRALGQNK | AHTPFRESKL | TQVLRDSFIG | 
    600:
    ENSRTCMIAM | ISPGISSCEY | TLNTLRYADR | VKELSPHSGP | SGEQPVQMET | 
    650:
    EVMEASSNGT | SLTGNEEEEL | SSQMSSFNEA | MTQIRELEER | ALEELREIIQ | 
    700:
    QGPNWLELSE | MTDQPDYDLE | TFVNKAESAL | TQQAKQAKHF | SALREVIKAL | 
    721:
    RLAMQLEEQA | SKQINSKKRH | Q
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Kinesin-like protein KIF2C
    ELISA Kit for Mouse Kinesin-like protein KIF2C
    ELISA Kit for Mouse Kinesin-like protein KIF2C
    CLIA Kit for Mouse Kinesin-like protein KIF2C
    CLIA Kit for Mouse Kinesin-like protein KIF2C
    CLIA Kit for Mouse Kinesin-like protein KIF2C
    Polyclonal Antibody for Mouse Kinesin-like protein KIF2C
    Polyclonal Antibody for Mouse Kinesin-like protein KIF2C
    Polyclonal Antibody for Mouse Kinesin-like protein KIF2C
    Monoclonal Antibody for Mouse Kinesin-like protein KIF2C
    Monoclonal Antibody for Mouse Kinesin-like protein KIF2C
    Monoclonal Antibody for Mouse Kinesin-like protein KIF2C
    Protein for Mouse Kinesin-like protein KIF2C
    Protein for Mouse Kinesin-like protein KIF2C
    Protein for Mouse Kinesin-like protein KIF2C

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops."
      Ogawa T. , Nitta R. , Okada Y. , Hirokawa N.
      Cell116:591-602(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS) OF 183-585 IN COMPLEX WITH ADP AND ATP ANALOG;FUNCTION;MUTAGENESIS OF LYS-293; VAL-294 AND ASP-295
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