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Index > Protein center > KLHDC2(Gene name) > Human
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  • KLHDC2 (Gene name),
  • Kelch domain-containing protein 2 (Protein name ),  KLDC2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    KLHDC2(HCA33);
    Protein name:
    Kelch domain-containing protein 2;
    Alternative:
    Host cell factor homolog LCP;Hepatocellular carcinoma-associated antigen 33;Host cell factor-like protein 1(HCLP-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Directly interacts with CREB3, but not with CREB1, ATF4, ATF6, JUN, FOS, CEBPA and herpes simplex virus transactivator VP16.
    Function:
    Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    406
    Sequence:
    50:
    MADGNEDLRA | DDLPGPAFES | YESMELACPA | ERSGHVAVSD | GRHMFVWGGY | 
    100:
    KSNQVRGLYD | FYLPREELWI | YNMETGRWKK | INTEGDVPPS | MSGSCAVCVD | 
    150:
    RVLYLFGGHH | SRGNTNKFYM | LDSRSTDRVL | QWERIDCQGI | PPSSKDKLGV | 
    200:
    WVYKNKLIFF | GGYGYLPEDK | VLGTFEFDET | SFWNSSHPRG | WNDHVHILDT | 
    250:
    ETFTWSQPIT | TGKAPSPRAA | HACATVGNRG | FVFGGRYRDA | RMNDLHYLNL | 
    300:
    DTWEWNELIP | QGICPVGRSW | HSLTPVSSDH | LFLFGGFTTD | KQPLSDAWTY | 
    350:
    CISKNEWIQF | NHPYTEKPRL | WHTACASDEG | EVIVFGGCAN | NLLVHHRAAH | 
    400:
    SNEILIFSVQ | PKSLVRLSLE | AVICFKEMLA | NSWNCLPKHL | LHSVNQRFGS | 
    406:
    NNTSGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    String:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Kelch domain-containing protein 2
    ELISA Kit for Human Kelch domain-containing protein 2
    ELISA Kit for Human Kelch domain-containing protein 2
    ELISA Kit for Human Kelch domain-containing protein 2
    CLIA Kit for Human Kelch domain-containing protein 2
    CLIA Kit for Human Kelch domain-containing protein 2
    CLIA Kit for Human Kelch domain-containing protein 2
    CLIA Kit for Human Kelch domain-containing protein 2
    Polyclonal Antibody for Human Kelch domain-containing protein 2
    Polyclonal Antibody for Human Kelch domain-containing protein 2
    Polyclonal Antibody for Human Kelch domain-containing protein 2
    Polyclonal Antibody for Human Kelch domain-containing protein 2
    Monoclonal Antibody for Human Kelch domain-containing protein 2
    Monoclonal Antibody for Human Kelch domain-containing protein 2
    Monoclonal Antibody for Human Kelch domain-containing protein 2
    Monoclonal Antibody for Human Kelch domain-containing protein 2
    Protein for Human Kelch domain-containing protein 2
    Protein for Human Kelch domain-containing protein 2
    Protein for Human Kelch domain-containing protein 2
    Protein for Human Kelch domain-containing protein 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Inhibition of LZIP-mediated transcription through direct interaction with a novel host cell factor-like protein."
      Zhou H.-J. , Wong C.-M. , Chen J.-H. , Qiang B.-Q. , Yuan J.-G. , Jin D.-Y.
      J. Biol. Chem.276:28933-28938(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH CREB3;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    2. 2.
      "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies."
      Wang Y. , Han K.-J. , Pang X.-W. , Vaughan H.A. , Qu W. , Dong X.-Y. , Peng J.-R. , Zhao H.-T. , Rui J.-A. , Leng X.-S. , Cebon J. , Burgess A.W. , Chen W.-F.
      J. Immunol.169:1102-1109(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Hepatoma.
    3. 3.
      "Full-length cDNA libraries and normalization."
      Li W.B. , Gruber C. , Jessee J. , Polayes D.
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Placenta.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Ovarian carcinoma.
    5. 5.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Kidney.
    8. 8.
      "Differential subcellular localization and activity of kelch repeat proteins KLHDC1 and KLHDC2."
      Chin K.-T. , Xu H.-T. , Ching Y.-P. , Jin D.-Y.
      Mol. Cell. Biochem.296:109-119(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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