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Index > Protein center > Klhl21(Gene name) > Rat
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  • Klhl21 (Gene name),
  • Kelch-like protein 21 (Protein name ),  KLH21_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Klhl21;
    Protein name:
    Kelch-like protein 21;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Component of the BCR(KLHL21) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL21 and RBX1.
    Function:
    Substrate-specific adapter of BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
    Subcellular Location:
    Cytoplasm cytoskeleton spindle Localizes to the spindle midzone and targets CUL3 to this region.
    Protein Attributes:
    Sequence length:
    597
    Sequence:
    50:
    MERPAPLAVL | PFSDPAHALS | LLRGLSQLRA | ERKFLDVTLE | AAGGRDFPAH | 
    100:
    RAVLAAASPY | FRAMFAGQLR | ESRAERVRLH | GVPPDMLQLL | LDFSYTGRVA | 
    150:
    VSGDNAEPLL | RAADLLQFPA | VKEACGAFLQ | QQLDLANCLD | MQDFAEAFSC | 
    200:
    SGLASAAQRF | ILRHVGELGA | EQLERLPLAR | LLRYLRDDGL | CVPKEEAAYQ | 
    250:
    LALRWVRADP | PRRAAHWPQL | LEAVRLPFVR | RFYLLAHVEA | EPLVARCPPC | 
    300:
    LRLLREARDF | QAARYDRHDR | GPCPRMRPRP | STGLAEILVL | VGGCDQDCDE | 
    350:
    LVTVDCYNPQ | TGQWRYLAEF | PDHLGGGYSI | VALGNDIYVT | GGSDGSRLYD | 
    400:
    CVWRYNSSVN | EWTEVAPMLK | AREYHSSSVL | NGLLYVVAAD | STERYDHATD | 
    450:
    SWEALQPMTY | PMDNCSTTAC | RGRLYAIGSL | AGKETMVIQC | YDPDTDLWSM | 
    500:
    VNCGQLPPWS | FAPKTVTLNG | LMYFVRDDSA | EVDVYNPTKD | EWDKIPSMNQ | 
    550:
    VHVGGSLAAL | GGKLYVSGGY | DNTFELSDVV | EAYDPETRAW | SVVGRLPEPT | 
    597:
    FWHGSVSIFR | QFMPQTPAGG | RGFELNSGSS | DVDAGHHRLP | QNPEELQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Kelch-like protein 21
    ELISA Kit for Rat Kelch-like protein 21
    ELISA Kit for Rat Kelch-like protein 21
    ELISA Kit for Rat Kelch-like protein 21
    CLIA Kit for Rat Kelch-like protein 21
    CLIA Kit for Rat Kelch-like protein 21
    CLIA Kit for Rat Kelch-like protein 21
    CLIA Kit for Rat Kelch-like protein 21
    Polyclonal Antibody for Rat Kelch-like protein 21
    Polyclonal Antibody for Rat Kelch-like protein 21
    Polyclonal Antibody for Rat Kelch-like protein 21
    Polyclonal Antibody for Rat Kelch-like protein 21
    Monoclonal Antibody for Rat Kelch-like protein 21
    Monoclonal Antibody for Rat Kelch-like protein 21
    Monoclonal Antibody for Rat Kelch-like protein 21
    Monoclonal Antibody for Rat Kelch-like protein 21
    Protein for Rat Kelch-like protein 21
    Protein for Rat Kelch-like protein 21
    Protein for Rat Kelch-like protein 21
    Protein for Rat Kelch-like protein 21

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    References
    1. 1.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
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