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Index > Protein center > KLK5(Gene name) > Human
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  • KLK5 (Gene name),
  • Kallikrein-5 (Protein name ),  KLK5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    KLK5(UNQ570/PRO1132;SCTE);
    Protein name:
    Kallikrein-5;
    Alternative:
    Stratum corneum tryptic enzyme;Kallikrein-like protein 2(KLK-L2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with SPINK9.
    Function:
    May be involved in desquamation.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    293
    Sequence:
    50:
    MATARPPWMW | VLCALITALL | LGVTEHVLAN | NDVSCDHPSN | TVPSGSNQDL | 
    100:
    GAGAGEDARS | DDSSSRIING | SDCDMHTQPW | QAALLLRPNQ | LYCGAVLVHP | 
    150:
    QWLLTAAHCR | KKVFRVRLGH | YSLSPVYESG | QQMFQGVKSI | PHPGYSHPGH | 
    200:
    SNNLMLIKLN | RRIRPTKDVR | PINVSSHCPS | AGTKCLVSGW | GTTKSPQVHF | 
    250:
    PKVLQCLNIS | VLSQKRCEDA | YPRQIDDTMF | CAGDKAGRDS | CQGDSGGPVV | 
    293:
    CNGSLQGLVS | WGDYPCARPN | RPGVYTNLCK | FTKWIQETIQ | ANS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Kallikrein-5
    Cat.:
    E1163h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Kallikrein-5
    Cat.:
    U1163h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Kallikrein-5
    Cat.:
    P1163Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Kallikrein-5
    Protein for Human Kallikrein-5

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation."
      Brattsand M. , Egelrud T.
      J. Biol. Chem.274:30033-30040(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ASP-153
      tissue: Stratum corneum.
    2. 2.
      "Identification of novel human kallikrein-like genes on chromosome 19q13.3-q13.4."
      Yousef G.M. , Luo L.-Y. , Diamandis E.P.
      Anticancer Res.19:2843-2852(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASP-153
    3. 3.
      "Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region."
      Gan L. , Lee I. , Smith R. , Argonza-Barrett R. , Lei H. , McCuaig J. , Moss P. , Paeper B. , Wang K.
      Gene257:119-130(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASP-153
    4. 4.
      "Differential expression of a human kallikrein 5 (KLK5) splice variant in ovarian and prostate cancer."
      Kurlender L. , Yousef G.M. , Memari N. , Robb J.D. , Michael I.P. , Borgono C. , Katsaros D. , Stephan C. , Jung K. , Diamandis E.P.
      Tumor Biol.25:149-156(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ASP-153
    5. 5.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASP-153
    6. 6.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASP-153
    7. 7.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ASP-153
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASP-153
      tissue: Ovary.
    10. 10.
      "SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor."
      Brattsand M. , Stefansson K. , Hubiche T. , Nilsson S.K. , Egelrud T.
      J. Invest. Dermatol.129:1656-1665(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SPINK9
    11. 11.
      "Identification of lympho-epithelial Kazal-type inhibitor 2 in human skin as a kallikrein-related peptidase 5-specific protease inhibitor."
      Meyer-Hoffert U. , Wu Z. , Schroeder J.M.
      PLoS ONE4:E4372-E4372(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    12. 12.
      "Structural basis of the zinc inhibition of human tissue kallikrein 5."
      Debela M. , Goettig P. , Magdolen V. , Huber R. , Schechter N.M. , Bode W.
      J. Mol. Biol.373:1017-1031(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 67-293 ALONE AND IN COMPLEX WITH ZINC;ENZYME REGULATION;ACTIVE SITE;GLYCOSYLATION AT ASN-208;DISULFIDE BONDS
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